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Patent Searching and Data


Title:
SUBSTITUTED PIPERAZINE COMPOUNDS AND METHODS OF USE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/192657
Kind Code:
A1
Abstract:
The invention relates to substituted piperazine compounds and methods of use and uses thereof, and further to the pharmaceutical compositions comprising the compounds and uses thereof, wherein the compound has Formula (I) or a stereoisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof. The substituted piperazine compounds and pharmaceutical compositions comprising the compounds disclosed herein can be used for inhibiting 5-hydroxytryptamine reuptake and/or stimulating 5-HT1A receptors. The invention also relates to processes for preparing these compounds and pharmaceutical compositions, and their uses in the treatment of a central nervous system dysfunction.

Inventors:
ZHANG YINGJUN (CN)
JIN CHUANFEI (CN)
LIANG HAIPING (CN)
YI CHAO (CN)
ZHANG JI (CN)
Application Number:
PCT/CN2016/084564
Publication Date:
December 08, 2016
Filing Date:
June 02, 2016
Export Citation:
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Assignee:
SUNSHINE LAKE PHARMA CO LTD (CN)
International Classes:
C07D403/12; A61K31/496; A61K31/506; A61P15/00; A61P19/00; A61P21/00; A61P25/00; C07D401/12
Domestic Patent References:
WO1995035293A11995-12-28
Foreign References:
CN105085482A2015-11-25
Attorney, Agent or Firm:
TSINGYIHUA INTELLECTUAL PROPERTY LLC (Trade Building Zhaolanyuan, Tsinghua University, Qinghuayuan, Haidian District, Beijing 4, CN)
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