Title:
SUBSTITUTED PROP-2-EN-1-ONE COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF
Document Type and Number:
WIPO Patent Application WO/2019/076190
Kind Code:
A1
Abstract:
The present invention relates to a substituted prop-2-en-1-one compound as shown in formula (I), and a pharmaceutically acceptable salt, polymorph, tautomer, stereoisomer, hydrate, solvate or isotopic variant thereof. Since the compound is a PPAR α and PPAR δ agonist, it can be used in a method for treating and/or preventing diseases caused by the PPAR α and/or PPAR δ, for example, in a therapeutic method of nonalcoholic steatohepatitis. Also provided in the present invention is a pharmaceutical composition comprising the compound of the present invention.
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Inventors:
WANG YIHAN (CN)
LI HUANYIN (CN)
LI HUANYIN (CN)
Application Number:
PCT/CN2018/108707
Publication Date:
April 25, 2019
Filing Date:
September 29, 2018
Export Citation:
Assignee:
SHENZHEN TARGETRX INC (CN)
International Classes:
C07C321/28; A61K31/192; A61P1/16; A61P3/06; A61P3/10; A61P9/10; A61P9/12; A61P43/00
Domestic Patent References:
| WO2017143038A1 | 2017-08-24 |
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