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Patent Searching and Data


Title:
SUBSTITUTED PROPANAMIDE DERIVATIVES, PREPARATION AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2007/009389
Kind Code:
A3
Abstract:
The present invention provides compounds of formula (I), the preparation thereof and their use as peroxisome proliferator activated receptor-γ (PPAR-γ) agonist in the treatment of diabetes and diabetic complications.

Inventors:
WANG MINGWEI (CN)
LIU QING (CN)
ZHOU CAIHONG (CN)
WU BIN (CN)
HUI XIN (CN)
Application Number:
PCT/CN2006/001784
Publication Date:
April 19, 2007
Filing Date:
July 20, 2006
Export Citation:
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Assignee:
SHANGHAI INST MATERIA MEDICA (CN)
WANG MINGWEI (CN)
LIU QING (CN)
ZHOU CAIHONG (CN)
WU BIN (CN)
HUI XIN (CN)
International Classes:
C07C235/34; A61K31/16; A61K31/265; A61K31/277; A61K31/341; A61K31/351; A61K31/381; A61K31/40; A61K31/421; A61K31/435; A61P5/50; C07C231/12; C07C235/30; C07C237/20; C07C255/32; C07C327/40; C07C333/04; C07D207/32; C07D213/04; C07D263/32; C07D307/34; C07D309/34
Domestic Patent References:
WO2004099150A22004-11-18
Foreign References:
GB1434090A1976-04-28
Other References:
SHIRAISHI T. ET AL.: "Specific Inhibitors of Tyrosine-Specific Protein Kinase. I. Synthesis and Inhibitory of alpha-Cyanocinnamamides", CHEM. PHARM. BULL, vol. 36, no. 3, 1988, pages 974 - 981
WELLS G. ET AL.: "Structural Studies on bioactive Compounds. 32. Oxidation of Tyrphostin Protein Tyrosine Kinase Inhibitors with Hypervalent Iodine Reagents", J. MED. CHEM., vol. 43, no. 8, 2000, pages 1550 - 1562, XP003010625
Attorney, Agent or Firm:
SHANGHAI KAIJI INTELLECTUAL PROPERTY AGENT CO., LTD. (188 Nandandong Road, Shanghai 0, CN)
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