Title:
SUBSTITUTED QUINAZOLINE COMPOUND, AND PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/254464
Kind Code:
A1
Abstract:
A substituted quinazoline compound, and a preparation method therefor, a pharmaceutical composition thereof, and a use thereof. Specifically, the present invention relates to a substituted quinazoline compound having BRK and/or BTK kinase inhibitory activity, a pharmaceutically acceptable salt or pharmaceutically acceptable solvate thereof, a preparation method therefor, a pharmaceutical composition comprising the compound, and the uses of these compounds in the preparation of a medication for preventing or treating a disease associated with a BRK kinase, a BTK kinase, or both in an organism.
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Inventors:
DENG XIANMING (CN)
HUANG WEI (CN)
SHENG SHEN (CN)
YUN CAIHONG (CN)
ZHANG JIANMING (CN)
HUANG XIN (CN)
HUANG WEI (CN)
SHENG SHEN (CN)
YUN CAIHONG (CN)
ZHANG JIANMING (CN)
HUANG XIN (CN)
Application Number:
PCT/CN2021/100775
Publication Date:
December 23, 2021
Filing Date:
June 18, 2021
Export Citation:
Assignee:
HONGYUN BIOTECH CO LTD (CN)
International Classes:
C07D239/84; A61K31/517; A61P35/00; C07D401/12; C07D401/14
Domestic Patent References:
WO2021013084A1 | 2021-01-28 | |||
WO2006039718A2 | 2006-04-13 | |||
WO2009046448A1 | 2009-04-09 | |||
WO2019204768A1 | 2019-10-24 |
Foreign References:
CN103140480A | 2013-06-05 | |||
CN109305944A | 2019-02-05 |
Attorney, Agent or Firm:
CCPIT PATENT AND TRADEMARK LAW OFFICE (CN)
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