Title:
SUBSTITUTED QUINOLINE COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF
Document Type and Number:
WIPO Patent Application WO/2017/202206
Kind Code:
A1
Abstract:
The present invention discloses a substituted quinoline compound as shown in formula (I), a pharmaceutical composition comprising said compound or a polymorph, a pharmaceutically acceptable salt, a prodrug, a stereoisomer, an isotopic variant, a hydrate, or a solvate of same, and an application thereof. The substituted quinoline compound disclosed in the present invention and the pharmaceutical composition comprising said compound can act as a 5-HT6 receptor antagonist, having good pharmacokinetic parameter characteristics, and being able to be used for preparing medicine for the treatment of Alzheimer's disease.
Inventors:
WANG YIHAN (CN)
LI HUANYIN (CN)
LI HUANYIN (CN)
Application Number:
PCT/CN2017/083878
Publication Date:
November 30, 2017
Filing Date:
May 11, 2017
Export Citation:
Assignee:
SHENZHEN TARGETRX INC (CN)
International Classes:
C07D215/40; A61K31/496; A61P3/04; A61P9/10; A61P25/14; A61P25/18; A61P25/22; A61P25/24; A61P25/28; C07B59/00
Foreign References:
| CN1656075A | 2005-08-17 |
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