SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF

Title:

SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF

Document Type and Number:

WIPO Patent Application WO/2014/143799

Kind Code:

A3

Abstract:

Compounds, compositions and methods are described for inhibiting the TRPC5 ion channel and disorders related to TRPC5.

More Like This:

WO/2012/085501	8 - SULFO - IMIDAZOTETRAZIN- 4 - ONE COMPOUNDS AND THEIR USE AS ANTICANCER DRUG
WO/2012/117027	6,7-DIHYDRO-PYRAZOLO[1,5-A]PYRAZIN-4-YLAMINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE (BACE)
WO/2015/081783	PYRROLO[2,1-F][1,2,4]TRIAZINE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF

Inventors:

CHENARD BERTRAND (US)
GALLASCHUN RANDALL (US)

Application Number:

PCT/US2014/027920

Publication Date:

November 06, 2014

Filing Date:

March 14, 2014

Export Citation:

Click for automatic bibliography generation Help

Assignee:

HYDRA BIOSCIENCES INC (US)

International Classes:

C07D487/04; A61K31/519; A61P25/00; C07D487/12

Domestic Patent References:

WO2011114184A1

2011-09-22

Other References:

YOSHIDA J ET AL: "Capacitative Ca<2+> entries and mRNA expression for TRPC1 and TRPC5 channels in human epidermoid carcinoma A431 cells", EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER SCIENCE, NL, vol. 510, no. 3, 14 March 2005 (2005-03-14), pages 217 - 222, XP027695255, ISSN: 0014-2999, [retrieved on 20050314]
KIM ET AL: "Molecular determinant of sensing extracellular pH in classical transient receptor potential channel 5", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 365, no. 2, 5 November 2007 (2007-11-05), pages 239 - 245, XP022356980, ISSN: 0006-291X, DOI: 10.1016/J.BBRC.2007.10.154

Attorney, Agent or Firm:

GEORGES EVANGELINOS, Asimina, T. (Riverfront Office ParkOne Main Street, Suite 110, Cambridge MA, US)

Download PDF:

View/Download PDF PDF Help

Previous Patent: REDUNDANT BUS FAULT DETECTION

Next Patent: CLAD SHEET ALLOYS FOR BRAZING APPLICATIONS