Title:
SUGAR ALCOHOL GRANULE AGGREGATE AND METHOD FOR PREPARING THE SAME
Document Type and Number:
WIPO Patent Application WO/2000/066171
Kind Code:
A1
Abstract:
A sugar alcohol granule for direct compression processing, a preparation method therefor, and a drug and a food comprising the same which can be rapidly disintegrated in a mouth. A granule aggregate containing sugar alcohol in an amount of 95 wt % or more, characterized in that 95 wt % or more of the aggregate is present as particles of 710 $g(m)m or less and 70 wt % or more of the aggregate as those of 75 to 710 $g(m)m, and the aggregate has a bulk density of 0.5 g/ml or more and an angle of repose of 40° or less. A sugar alcohol granule aggregate, and a method of preparing the granule aggregate comprising a step charging a sugar alcohol powder on a circular plate rotating in a treating chamber of a centrifugal rolling granulating apparatus and spraying an aqueous solution while supplying a slit air to the chamber and rotating the circular plate to thereby carry out a wet granulation, and a step drying the resulting wet granule in a fluidized bed.
Inventors:
TANAI IKUO (JP)
KATO HISAYOSHI (JP)
KATO HISAYOSHI (JP)
Application Number:
PCT/JP1999/002809
Publication Date:
November 09, 2000
Filing Date:
May 27, 1999
Export Citation:
Assignee:
FREUNT IND CO LTD (JP)
TANAI IKUO (JP)
KATO HISAYOSHI (JP)
TANAI IKUO (JP)
KATO HISAYOSHI (JP)
International Classes:
A23L1/09; A23P1/02; A61K9/00; A61K9/16; (IPC1-7): A61K47/26; A23P1/02; A61K9/14; A61K9/16; A61K9/20
Foreign References:
| JPH1036291A | 1998-02-10 | |||
| JPS61155343A | 1986-07-15 | |||
| JPH09263589A | 1997-10-07 | |||
| JPH06205959A | 1994-07-26 |
Attorney, Agent or Firm:
Hiraki, Yusuke (Toranomon 1-chome Minato-ku Tokyo, JP)
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