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Title:
SUGAR CHAIN LIGAND COMPOSITE AND METHOD OF ANALYZING PROTEIN WITH THE LIGAND COMPOSITE
Document Type and Number:
WIPO Patent Application WO/2005/077965
Kind Code:
A1
Abstract:
A novel ligand composite which is effectively utilizable for analyzing a function of a protein; a ligand-supporting object; and a method of analyzing a protein. The ligand composite has a structure which comprises: a linker compound having a structure represented by the following general formula (1): (wherein n and p each is an integer of 0 to 6) in which X is a structure comprising one, two, or three hydrocarbon derivative chains which have an aromatic amino group at the end and may have a carbon-nitrogen bond in the main chain, Y is a hydrocarbon structure containing one or more sulfur atoms, and Z is a linear structure comprising a carbon-carbon bond or carbon-oxygen bond; and a sugar which has a reducing end and is bonded to the linker compound through the aromatic amino group.

Inventors:
SUDA YASUO
Application Number:
PCT/JP2005/003220
Publication Date:
August 25, 2005
Filing Date:
February 18, 2005
Export Citation:
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Assignee:
JAPAN SCIENCE & TECH AGENCY (JP)
NAT UNIV CORP KAGOSHIMA (JP)
SUDA YASUO
International Classes:
C07H15/04; G01N33/531; (IPC1-7): C07H15/04; C07D339/04; G01N27/62; G01N33/53
Domestic Patent References:
WO2004022583A12004-03-18
Foreign References:
JP2003083969A2003-03-19
Other References:
SUDA Y. ET AL: "oligosaccharide Chain no Nano Level Kino Kaisei System no Kaihatsu.", THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH., vol. 24, 2003, pages 36, XP002991262
KONO A. ET AL: "Ryusana Oligosaccharide o Shugoka shite Koteika shita Sugar Chip no Chosei to SPR-ho eno Oyo.", THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH NENKAI YOSHISHU., vol. 24, 2003, pages 127, XP002991804
KONO A. ET AL: "Heparin Bubun Kozo o Yusuru Cluster-ka Oligosaccharide Ligand no Gosei to Chip Technology eno Oyo.", THE CHEMICAL SOCIETY OF JAPAN KOEN YOKOSHU., vol. 82, 2002, pages 137, XP002991805
Attorney, Agent or Firm:
HARAKENZO WORLD PATENT & TRADEMARK (2-6 Tenjinbashi 2-chome Kita, Kita-k, Osaka-shi Osaka 41, JP)
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