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Title:
SULPHAMIDE DERIVATIVE HAVING AN ADAMANTYL GROUP AND A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF
Document Type and Number:
WIPO Patent Application WO/2012/134233
Kind Code:
A3
Abstract:
Provided is a sulphamide derivative having an adamantyl group, represented by the accompanying chemical formula 1, or a pharmaceutically acceptable salt thereof. The sulphamide derivative suppresses the activity of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), and is useful in the treatment of various diseases that are mediated by 11β-HSD1.

Inventors:
KIM KI YOUNG (KR)
AHN JIN HEE (KR)
KANG SEUNG KYU (KR)
BAE MYUNG AE (KR)
AHN SUNG HOON (KR)
KIM HEE YOUN (KR)
JUNG WON HOON (KR)
KANG NAM SOOK (KR)
Application Number:
PCT/KR2012/002407
Publication Date:
January 10, 2013
Filing Date:
March 30, 2012
Export Citation:
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Assignee:
KOREA RES INST CHEM TECH (KR)
SK BIOPHARMACEUTICALS CO LTD (KR)
KIM KI YOUNG (KR)
AHN JIN HEE (KR)
KANG SEUNG KYU (KR)
RHEE SANG DAL (KR)
BAE MYUNG AE (KR)
AHN SUNG HOON (KR)
KIM HEE YOUN (KR)
JUNG WON HOON (KR)
KANG NAM SOOK (KR)
International Classes:
C07C307/06; A61K31/18; A61P3/10
Domestic Patent References:
WO2011044370A12011-04-14
WO2007057768A22007-05-24
Foreign References:
US7842707B22010-11-30
Other References:
KIM, SE HOAN ET AL.: "Synthesis and Biological Evaluation of Cyclic Sulfamide Derivatives as 11beta-Hydroxysteroid Dehydrogenase 1 Inhibitors", ACS MEDICINAL CHEMISTRY LETTERS, vol. 3, no. 2, 17 January 2012 (2012-01-17), pages 88 - 93, XP055128544
Attorney, Agent or Firm:
YANG, Boo-Hyun (1659-2 Inhundong Gwanak-gu, Seoul 151-832, KR)
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Claims: