Title:
SUPERCRITICAL FLUID LOADING OF POROUS MEDICAL DEVICES WITH BIOACTIVE AGENTS
Document Type and Number:
WIPO Patent Application WO/2010/039644
Kind Code:
A3
Abstract:
Described herein are implantable medical devices that can be coated with polymers and/or bioactive agents with the aid of supercritical fluids and methods for coating the devices. The medical devices described herein can have at least a portion of their surface made of or formed from a porous material. The supercritical fluids are used as a carrier for the bioactive agents described. Once the bioactive agents are carried to the medical device surface, they are sequestered there, preferably in the pores. The supercritical fluid is sprayed onto the medical devices achieving precipitation of the fluid. If appropriate conditions are used in the area of precipitation, bioactive agents can penetrate into the pores of the medical device before coming out of solution and expanding.
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Inventors:
BERGLUND JOSEPH (US)
Application Number:
PCT/US2009/058585
Publication Date:
December 29, 2010
Filing Date:
September 28, 2009
Export Citation:
Assignee:
MEDTRONIC VASCULAR INC (US)
BERGLUND JOSEPH (US)
BERGLUND JOSEPH (US)
International Classes:
A61L27/34; A61L27/54; A61L29/08; A61L29/16; A61L31/10; A61L31/16; B05D1/02
Domestic Patent References:
| WO2006063158A2 | 2006-06-15 | |||
| WO1994018264A1 | 1994-08-18 |
Foreign References:
| US20020155145A1 | 2002-10-24 |
Attorney, Agent or Firm:
SHELDON, Anthony (3576 Unocal PlaceSanta Rosa, California, US)
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