Title:
SUPEROXIDE-GENERATING DIAZENIUMDIOLATES, COMPOSITIONS COMPRISING SAME, AND METHODS FOR USING SAME
Document Type and Number:
WIPO Patent Application WO2001092215
Kind Code:
A3
Abstract:
The invention provides a compounds comprising a [N(O)NO] functional group and a superoxide-generating moiety, wherein said compound is capable of generating nitric oxide and superoxide. The invention also provides compositions comprising same and methods of using same.
Inventors:
BONIFANT CHALLICE (US)
SAAVEDRA JOSEPH (US)
KEEFER LARRY (US)
CITRO MICHAEL (US)
BUZARD GREGORY (US)
FITZHUGH ANTHONY (US)
DONOVAN PAUL (US)
JI XINHUA (US)
SHAMI PAUL (US)
SINGH SHIVENDRA (US)
SRINIVASAN ALOKA (US)
SAAVEDRA JOSEPH (US)
KEEFER LARRY (US)
CITRO MICHAEL (US)
BUZARD GREGORY (US)
FITZHUGH ANTHONY (US)
DONOVAN PAUL (US)
JI XINHUA (US)
SHAMI PAUL (US)
SINGH SHIVENDRA (US)
SRINIVASAN ALOKA (US)
Application Number:
PCT/US2001/017868
Publication Date:
June 27, 2002
Filing Date:
June 01, 2001
Export Citation:
Assignee:
US HEALTH (US)
BONIFANT CHALLICE (US)
SAAVEDRA JOSEPH (US)
KEEFER LARRY (US)
CITRO MICHAEL (US)
BUZARD GREGORY (US)
FITZHUGH ANTHONY (US)
DONOVAN PAUL (US)
JI XINHUA (US)
SHAMI PAUL (US)
SINGH SHIVENDRA (US)
SRINIVASAN ALOKA (US)
BONIFANT CHALLICE (US)
SAAVEDRA JOSEPH (US)
KEEFER LARRY (US)
CITRO MICHAEL (US)
BUZARD GREGORY (US)
FITZHUGH ANTHONY (US)
DONOVAN PAUL (US)
JI XINHUA (US)
SHAMI PAUL (US)
SINGH SHIVENDRA (US)
SRINIVASAN ALOKA (US)
International Classes:
C07C291/02; C07C291/08; C07D207/50; C07D233/60; C07D521/00; C08G73/02; (IPC1-7): C07C291/08; A61K31/085; A61K31/235; A61K31/4164; C07D207/50; C07D233/60
Domestic Patent References:
| WO1998013358A1 | 1998-04-02 |
Foreign References:
| US5405919A | 1995-04-11 |
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