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Title:
SUPPORT FOR AFFINITY CHROMATOGRAPHY AND METHOD FOR ISOLATING IMMUNOGLOBULIN
Document Type and Number:
WIPO Patent Application WO/2012/086660
Kind Code:
A1
Abstract:
Provided are a support for affinity chromatography, which has excellent alkali resistance, and a method for isolating immunoglobulin. The support for affinity chromatography is a support, onto which a protein ligand represented by general formula (1): R-R2 has been immobilized. In general formula (1), R represents a polypeptide comprising 4 to 30 amino acid residues and containing an amino acid sequence represented by ATK or ASK, and R2 represents a polypeptide comprising 50 to 500 amino acid residues and containing an immunoglobulin-binding domain comprising an amino acid sequence represented by SEQ ID NO: 1 or 2, a partial sequence thereof, or an amino acid sequence having at least 70% homology therewith. (The end of R2 binding to R is the C- or N-terminus of the immunoglobulin-binding domain.)

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Inventors:
NAKAMURA SATOSHI (JP)
FUKUTA TETSUO (JP)
OKANO YUSUKE (JP)
SHIOTANI TOMONORI (JP)
TAMORI KOUJI (JP)
WANG YONG (JP)
LI SHUN-CHENG SHAWN (CA)
LI XING (CA)
VOSS COURTNEY (CA)
Application Number:
PCT/JP2011/079568
Publication Date:
June 28, 2012
Filing Date:
December 20, 2011
Export Citation:
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Assignee:
JSR CORP (JP)
UNIV WESTERN ONTARIO (CA)
NAKAMURA SATOSHI (JP)
FUKUTA TETSUO (JP)
OKANO YUSUKE (JP)
SHIOTANI TOMONORI (JP)
TAMORI KOUJI (JP)
WANG YONG (JP)
LI SHUN-CHENG SHAWN (CA)
LI XING (CA)
VOSS COURTNEY (CA)
International Classes:
C07K1/22; C07K16/00; C07K17/08; C12N15/09
Domestic Patent References:
WO2010110288A12010-09-30
WO2007097361A12007-08-30
WO2010035756A12010-04-01
Foreign References:
JP2008241560A2008-10-09
JP2010156687A2010-07-15
JP2006304633A2006-11-09
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
Patent business corporation Alga patent firm (JP)
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