SUPPORT FOR PROTEIN IMMOBILIZATION, IMMOBILIZED PROTEIN AND METHOD FOR PRODUCING SAME

Title:

SUPPORT FOR PROTEIN IMMOBILIZATION, IMMOBILIZED PROTEIN AND METHOD FOR PRODUCING SAME

Document Type and Number:

WIPO Patent Application WO/2011/155536

Kind Code:

A1

Abstract:

The object is to provide a support for enzyme immobilization, which is usable for immobilizing enzymes of various molecular sizes and also usable, due to the modification of the surface silanol group in porous silica particles, for immobilizing various kinds of enzymes, and enables the design of an immobilized enzyme, which exhibits an activity equivalent to the activity of a non-immobilized enzyme corresponding thereto and withstands repeated use, and a method for producing the same. Provided is a support for protein immobilization, which comprises porous silica particles having an interparticle void structure therein, characterized in that said porous silica particles have a specific average particle diameter, a specific specific surface area, a specific pore volume, a specific pore diameter distribution and a specific porosity and have a substituent containing an organic group or an amino group on the surface thereof. Also provided is an immobilized protein that is obtained by immobilizing a protein on the aforesaid support for protein immobilization.

Inventors:

TSUNODA TATSUO (JP)
NARA TAKAYUKI (JP)
ONO SEIGO (JP)
SEKIKAWA CHISATO (JP)
MIZUKAMI FUJIO (JP)
KOJIMA SHUZO (JP)
TAHARA NAOKI (JP)
TOGASHI HIDEAKI (JP)
EGAMI MIKI (JP)

Application Number:

PCT/JP2011/063160

Publication Date:

December 15, 2011

Filing Date:

June 08, 2011

Export Citation:

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Assignee:

JGC CATALYSTS & CHEMICALS LTD (JP)
NAT INST OF ADVANCED IND SCIEN (JP)
JGC CORP (JP)
TSUNODA TATSUO (JP)
NARA TAKAYUKI (JP)
ONO SEIGO (JP)
SEKIKAWA CHISATO (JP)
MIZUKAMI FUJIO (JP)
KOJIMA SHUZO (JP)
TAHARA NAOKI (JP)
TOGASHI HIDEAKI (JP)
EGAMI MIKI (JP)

International Classes:

C12N11/14; C01B37/00; C07K17/14

Foreign References:

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JP2010138021A	2010-06-24
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JP2009125006A	2009-06-11
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Other References: