Title:
SUPPRESSOR FOR INCREASE IN BLOOD GLUCOSE LEVEL
Document Type and Number:
WIPO Patent Application WO/2012/063820
Kind Code:
A1
Abstract:
The present invention relates to a suppressor for increase in postprandial blood glucose level, which contains an ester of EPA or DHA as an active ingredient and is characterized by being administered between meals. The present invention provides a suppressor for increase in blood glucose level which is highly safe and has desired properties including storage stability, particularly a means for preventing postprandial hyperglycemia.
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Inventors:
KANEHIRO HIDEO (JP)
IMAI MARIKO (JP)
IMAI MARIKO (JP)
Application Number:
PCT/JP2011/075723
Publication Date:
May 18, 2012
Filing Date:
November 08, 2011
Export Citation:
Assignee:
MOCHIDA PHARM CO LTD (JP)
NIPPON SUISAN KAISHA LTD (JP)
KANEHIRO HIDEO (JP)
IMAI MARIKO (JP)
NIPPON SUISAN KAISHA LTD (JP)
KANEHIRO HIDEO (JP)
IMAI MARIKO (JP)
International Classes:
A61K31/232; A23L33/00; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P9/12
Domestic Patent References:
| WO2005083070A1 | 2005-09-09 | |||
| WO1995024459A1 | 1995-09-14 | |||
| WO2007119811A1 | 2007-10-25 |
Other References:
MORISHITA M. ET AL.: "Usefulness of colon targeted DHA and EPA as novel diabetes medications that promote intrinsic GLP-1 secretion", J. CONTROL. RELEASE, vol. 132, no. 2, 2008, pages 99 - 104, XP025684665
ADACHI T. ET AL.: "Administration of perilla oil coated with Calshell increases glucagon-like peptide secretion", BIOL. PHARM. BULL., vol. 31, no. 5, 2008, pages 1021 - 1023, XP055084763
YASUFUMI SAWADA: "III. Compatibility between drug and meals. 9. Ethyl icosapentate or probucol and meals", MEDICINE AND DRUG JOURNAL, vol. 41, no. 6, 2005, pages 1659 - 1662
See also references of EP 2638903A4
F. TETSUHIRO ET AL.: "Effect of EPA administration on glucose metabolism in patients with NIDDM", JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE (IGAKU NO AYUMI, vol. 169, no. 8, 1994, pages 889 - 890
T. SHINJO ET AL.: "Effect of Epadel on diabetes", THE JAPANESE JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, vol. 71, no. 10, 1993, pages 2716 - 2718
MORISHITA ET AL.: "Usefulness of colon targeted DHA and EPA as novel diabetes medications that promote intrinsic GLP-1 secretion", JOURNAL OF CONTROLLED RELEASE, vol. 132, 2008, pages 99 - 104
ADACHI ET AL.: "Administration of Perilla Oil Coated with Calshell Increases Glucagon-Like Peptide Secretion", BIOL. PHARM. BULL., vol. 31, no. 5, 2008, pages 1021 - 1023
ADACHI T. ET AL.: "Administration of perilla oil coated with Calshell increases glucagon-like peptide secretion", BIOL. PHARM. BULL., vol. 31, no. 5, 2008, pages 1021 - 1023, XP055084763
YASUFUMI SAWADA: "III. Compatibility between drug and meals. 9. Ethyl icosapentate or probucol and meals", MEDICINE AND DRUG JOURNAL, vol. 41, no. 6, 2005, pages 1659 - 1662
See also references of EP 2638903A4
F. TETSUHIRO ET AL.: "Effect of EPA administration on glucose metabolism in patients with NIDDM", JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE (IGAKU NO AYUMI, vol. 169, no. 8, 1994, pages 889 - 890
T. SHINJO ET AL.: "Effect of Epadel on diabetes", THE JAPANESE JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, vol. 71, no. 10, 1993, pages 2716 - 2718
MORISHITA ET AL.: "Usefulness of colon targeted DHA and EPA as novel diabetes medications that promote intrinsic GLP-1 secretion", JOURNAL OF CONTROLLED RELEASE, vol. 132, 2008, pages 99 - 104
ADACHI ET AL.: "Administration of Perilla Oil Coated with Calshell Increases Glucagon-Like Peptide Secretion", BIOL. PHARM. BULL., vol. 31, no. 5, 2008, pages 1021 - 1023
Attorney, Agent or Firm:
ONO, Shinjiro et al. (JP)
Ono Shinjiro (JP)
Ono Shinjiro (JP)
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