Title:
SUPRAMOLECULAR NANOFIBERS AND HYDROGELS BASED ON AMINO ACID-NUCLEOBASE-GLYCOSIDE CONJUGATES
Document Type and Number:
WIPO Patent Application WO/2012/166705
Kind Code:
A3
Abstract:
Described herein are hydrogelators that include a nucleobase, an amino acid, and a glycoside. The hydrogelators have increased resistance to proteases and can self-assemble into supramolecular nanofibers or hydrogels. The supramolecular structures may be used to help grow cells or deliver a substance to a cell.
Inventors:
XU BING (US)
Application Number:
PCT/US2012/039821
Publication Date:
February 28, 2013
Filing Date:
May 29, 2012
Export Citation:
Assignee:
UNIV BRANDEIS (US)
XU BING (US)
XU BING (US)
International Classes:
C07H17/02; A61K31/706; A61K38/14; A61P35/00; C07H19/00
Foreign References:
| US20080057005A1 | 2008-03-06 | |||
| US5278284A | 1994-01-11 | |||
| US20020081726A1 | 2002-06-27 |
Other References:
LI, X. ET AL.: "Multifunctional, Biocompatible Supramolecular Hydrogelators Consist Only for Nucleobase, Amino Acid, and Glycoside", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, vol. 133, 19 September 2011 (2011-09-19), pages 17513 - 17518
YANG, Z. ET AL.: "Supramolecular hydrogels based on biofunctional nanofibers of self-assembled small molecules", JOURNAL OF MATERIALS CHEMISTRY, vol. 17, 2007, pages 2385 - 2393
YANG, Z. ET AL.: "Supramolecular hydrogels based on biofunctional nanofibers of self-assembled small molecules", JOURNAL OF MATERIALS CHEMISTRY, vol. 17, 2007, pages 2385 - 2393
Attorney, Agent or Firm:
GORDON, Dana, M. et al. (Patent Group155 Seaport Boulevar, Boston MA, US)
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