SUSTAINED-RELEASE HYDROGEL PREPARATION - YAMANOUCHI PHARMA CO LTD

Title:

SUSTAINED-RELEASE HYDROGEL PREPARATION

Document Type and Number:

WIPO Patent Application WO/1994/006414

Kind Code:

A1

Abstract:

A sustained-release hydrogen preparation comprising at least one drug, an additive for making water penetrate into the preparation and a macromolecular substance which forms hydrogel. It can nearly completely gel when it stays in the upper parts of the digestive tract, i.e. the stomach and small intestine, and can release the drug in the lower part thereof, i.e. the colon. The preparation enables the drug to be well dissolved and absorbed even in the colon, thus achieving a stable sustained-release effect.

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Inventors:

SAKO KAZUHIRO (JP)
NAKASHIMA HIROSHI (JP)
SAWADA TOYOHIRO (JP)
OKADA AKIRA (JP)
FUKUI MUNEO (JP)

Application Number:

PCT/JP1993/001297

Publication Date:

March 31, 1994

Filing Date:

September 10, 1993

Export Citation:

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Assignee:

YAMANOUCHI PHARMA CO LTD (JP)
SAKO KAZUHIRO (JP)
NAKASHIMA HIROSHI (JP)
SAWADA TOYOHIRO (JP)
OKADA AKIRA (JP)
FUKUI MUNEO (JP)

International Classes:

A61K9/20; A61K9/22; A61K47/34; (IPC1-7): A61K9/22; A61K47/34; A61K47/36

Foreign References:

JPH032119A	1991-01-08
JPH0334927A	1991-02-14
JPH04501411A	1992-03-12
JPH04217924A	1992-08-07

Other References: