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Title:
SUSTAINED-RELEASE MULTILAYER TABLET COMPRISING TICAGRELOR OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AS ACTIVE INGREDIENT, AND METHOD FOR PREPARING SAME
Document Type and Number:
WIPO Patent Application WO/2023/149642
Kind Code:
A1
Abstract:
The present invention relates to a sustained-release multilayer tablet comprising ticagrelor or a pharmaceutically acceptable salt thereof as an active ingredient, and a method for preparing same. When the tablet is administered orally, once a day, ticagrelor or a pharmaceutically acceptable salt thereof is released and absorbed in the body continuously for 24 hours, and thus, it is possible to improve convenience of administration. In addition, after oral administration, the tablet is not affected by the pH and amount of gastrointestinal fluid in the gastrointestinal tract and has an increased dissolution rate such that absorption occurs in all parts of the gastrointestinal tract, and thus, it is possible to maintain the concentration of a drug at a certain level or greater for a long time.

Inventors:
SUH HEARAN (KR)
KANG KYOUNG UN (KR)
LIM NAM HUN (KR)
KO DU YOUNG (KR)
LEE KWAN JUN (KR)
HEO JI YEON (KR)
Application Number:
PCT/KR2022/019789
Publication Date:
August 10, 2023
Filing Date:
December 07, 2022
Export Citation:
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Assignee:
POSTERA HEALTH SCIENCE INC (KR)
International Classes:
A61K9/24; A61K31/519; A61P7/02
Foreign References:
KR20200077956A2020-07-01
KR20150075961A2015-07-06
KR20190040764A2019-04-19
CN111991362A2020-11-27
KR20210057590A2021-05-21
Attorney, Agent or Firm:
WON, Dae Gyu (KR)
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