SUSTAINED-RELEASE PREPARATION USING GASTRORETENTIVE DRUG DELIVERY SYSTEM

WIPO Patent Application WO/2013/162114

A1

The present invention relates to a sustained-release preparation which limits release and absorption of drug using a gastroretentive system and which can minimize the effect of in vivo environment, and to a method for preparing the sustained-release preparation. More particularly, the sustained-release preparation according to the present invention comprises a swellable polymer, and a first controlled-release base and a second controlled-release base. Therefore, the sustained-release preparation of the present invention may adjust the degree of swelling and floating of a polymer in order to effectively achieve gastric retention. Thus, drugs may ultimately be retained in the gastrointestinal tract over a long period of time, and the bioavailability of drugs may be improved in order to enable once-a-day administration.

JP5940585	How to manufacture the above-mentioned wire with which the active substance was filled up into the hole formed in the system filled up with the hole in a medicine sending-out wire, and the wire
WO/1986/006627	SUSTAINED RELEASE THEOPHYLLINE COMPOSITIONS AND PROCESSES
JP2023078155	DOSAGE FORMS AND USE THEREOF

PARK YOUNG JOON (KR)
SHIN KYUNG MIN (KR)
JIN HONG CHUL (KR)
SUNG BO HYON (KR)
NOH HYUN JUNG (KR)
KIM SUNG JUN (KR)

PCT/KR2012/004001

October 31, 2013

May 21, 2012

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CJ CHEILJEDANG CORP (KR)
PARK YOUNG JOON (KR)
SHIN KYUNG MIN (KR)
JIN HONG CHUL (KR)
SUNG BO HYON (KR)
NOH HYUN JUNG (KR)
KIM SUNG JUN (KR)

A61K9/22; A61K9/20; A61K47/30; A61K47/38

KR20110046360A	2011-05-04
KR20110015650A	2011-02-16
KR20110123178A	2011-11-14
KR20110048317A	2011-05-11

SON, MIN (KR)
손민 (KR)

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