Title:
SUSTAINED RELEASE SUSPENSION CONTAINING DEZOCINE ANALOGUE ESTER AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2019/007441
Kind Code:
A1
Abstract:
Disclosed are a sustained release suspension containing dezocine analogue ester and a preparation method therefor. According to the present invention, an injectable oily auxiliary material which may pharmaceutically serve as a sustained-release depot and an excipient are selected, and micronization technology is used jointly with high pressure homogenization technology and an anti-solvent technique to prepare an injectable long-acting suspension. The main components of the suspension are a compound represented by formula (I), the injectable oil, and the like.
Inventors:
ZHANG YANG (CN)
DENG BING (CN)
WU JIAHU (CN)
WU WENTAO (CN)
LI ZHIXIANG (CN)
DENG BING (CN)
WU JIAHU (CN)
WU WENTAO (CN)
LI ZHIXIANG (CN)
Application Number:
PCT/CN2018/099232
Publication Date:
January 10, 2019
Filing Date:
August 07, 2018
Export Citation:
Assignee:
SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN)
International Classes:
A61K31/215; A61K9/00; A61P25/04
Domestic Patent References:
| WO2017118375A1 | 2017-07-13 | |||
| WO2012066347A1 | 2012-05-24 |
Foreign References:
| CN104274473A | 2015-01-14 | |||
| CN104523584A | 2015-04-22 |
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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