Title:
SYNAPSE FORMATION AGENT
Document Type and Number:
WIPO Patent Application WO/2017/188457
Kind Code:
A1
Abstract:
The present invention relates to a synapse formation accelerant and a brain plasticity accelerant that contain CD24-negative mesenchymal stem cells prepared from a patient's own bone marrow fluid, as well as to treatment of dementia, chronic cerebral infarctions, chronic spinal cord injuries, mental disorders, or the like using the aforementioned synapse formation accelerant and brain plasticity accelerant.
Inventors:
HONMOU OSAMU (JP)
SASAKI MASANORI (JP)
MAEZAWA RIE (JP)
OKA SHINICHI (JP)
SASAKI YUKO (JP)
NAKAZAKI MASAHITO (JP)
YAMASHITA TOSHIHIKO (JP)
SASAKI MASANORI (JP)
MAEZAWA RIE (JP)
OKA SHINICHI (JP)
SASAKI YUKO (JP)
NAKAZAKI MASAHITO (JP)
YAMASHITA TOSHIHIKO (JP)
Application Number:
PCT/JP2017/017325
Publication Date:
November 02, 2017
Filing Date:
April 26, 2017
Export Citation:
Assignee:
UNIV SAPPORO MEDICAL (JP)
NIPRO CORP (JP)
NIPRO CORP (JP)
International Classes:
A61K35/28; A61P25/00; A61P25/28
Foreign References:
| JP2012100662A | 2012-05-31 |
Other References:
GUTIERREZ-FERNANDES, MARIA ET AL.: "Effects of intravenous administration of allogenic bone marrow- and adipose tissue-derived mesenchymal stem cells on functional recovery and brain repair markers in experimental ischemic stroke", STEM CELL RESEARCH & THERAPY, vol. 4, no. 11, 2013, pages 1 - 12, XP021140601
OSAMU HONMO: "No Kosoku to Sekizui Sonsho no Saisei Iryo -Ishi Shudo Chiken ni yoru Jitsuyoka", THE HOKKAIDO JOURNAL OF OCCUPATIONAL THERAPY: HOKKAIDO SAGYO RYOHO, vol. 32, no. 1, 2015, pages 13 - 28, XP009516609, Retrieved from the Internet
See also references of EP 3449930A4
OSAMU HONMO: "No Kosoku to Sekizui Sonsho no Saisei Iryo -Ishi Shudo Chiken ni yoru Jitsuyoka", THE HOKKAIDO JOURNAL OF OCCUPATIONAL THERAPY: HOKKAIDO SAGYO RYOHO, vol. 32, no. 1, 2015, pages 13 - 28, XP009516609, Retrieved from the Internet
See also references of EP 3449930A4
Attorney, Agent or Firm:
OHNO, Seiji et al. (JP)
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