SYNTHESIS OF 2-ARYL-1-NAPHTHOL DERIVATIVES VIA A TANDEM PALLADIUM CATALYZED ARYLATION AND DEHYDROGENATION

Title:

SYNTHESIS OF 2-ARYL-1-NAPHTHOL DERIVATIVES VIA A TANDEM PALLADIUM CATALYZED ARYLATION AND DEHYDROGENATION

Document Type and Number:

WIPO Patent Application WO2002044119

Kind Code:

A8

Abstract:

The present invention relates to a one-pot process for preparing a compound of formula (I): I;by reacting a compound of formula (II) with a compound of formula (III): in the presence of a suitable solvent, a suitable base, a palladium catalyst and a suitable ligand.

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Inventors:

MAY SCOTT ALLAN (US)
WILSON THOMAS MICHAEL (US)
ZHANG TONY YANTAO (US)

Application Number:

PCT/US2001/042945

Publication Date:

November 20, 2003

Filing Date:

November 15, 2001

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Assignee:

LILLY CO ELI (US)
MAY SCOTT ALLAN (US)
WILSON THOMAS MICHAEL (US)
ZHANG TONY YANTAO (US)

International Classes:

C07C37/20; C07C39/14; C07C41/30; C07C43/23; C07D295/092; C07D295/13; (IPC1-7): C07C37/20; C07C41/30; C07C39/14; C07C43/23

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