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Title:
SYNTHESIS AND USE OF RETINOID COMPOUNDS HAVING NEGATIVE HORMONE AND/OR ANTAGONIST ACTIVITIES
Document Type and Number:
WIPO Patent Application WO1997009297
Kind Code:
A3
Inventors:
KLEIN ELLIOTT S (US)
JOHNSON ALAN T (US)
STANDEVEN ANDREW M (US)
BEARD RICHARD L (US)
GILLETT SAMUEL J (US)
DUONG TIEN T (US)
NAGPAL SUNIL (US)
VULIGONDA VIDYASAGAR (US)
TENG MIN (US)
CHANDRARATNA ROSHANTHA A (US)
Application Number:
US9613779W
Publication Date:
August 28, 1997
Filing Date:
August 23, 1996
Export Citation:
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Assignee:
ALLERGAN INC (US)
KLEIN ELLIOTT S (US)
JOHNSON ALAN T (US)
STANDEVEN ANDREW M (US)
BEARD RICHARD L (US)
GILLETT SAMUEL J (US)
DUONG TIEN T (US)
NAGPAL SUNIL (US)
VULIGONDA VIDYASAGAR (US)
TENG MIN (US)
CHANDRARATNA ROSHANTHA A (US)
International Classes:
C07D317/26; A61K31/15; A61K31/192; A61K31/215; A61K31/216; A61K31/341; A61K31/352; A61K31/357; A61K31/37; A61K31/381; A61K31/382; A61K31/426; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4418; A61K31/47; A61K38/09; A61P5/00; A61P39/02; C07C57/50; C07C63/33; C07C63/331; C07C63/49; C07C63/66; C07C63/72; C07C63/74; C07C65/19; C07C65/28; C07C65/38; C07C69/48; C07C69/618; C07C69/76; C07C69/773; C07C69/90; C07C69/94; C07C233/81; C07C245/10; C07C327/48; C07C335/06; C07C403/20; C07D213/55; C07D215/12; C07D277/20; C07D277/30; C07D307/54; C07D311/58; C07D333/24; C07D335/06; C07F7/08; C07C; C07D; (IPC1-7): C07C69/78; A61K31/215; C07C63/66; C07C69/94; C07C233/81; C07C327/48; C07D307/16; C07C245/10; C07C63/74; C07D277/30; C07D333/24; C07D213/55
Domestic Patent References:
WO1993021146A11993-10-28
WO1994014777A11994-07-07
Foreign References:
EP0661259A11995-07-05
EP0617020A11994-09-28
EP0478787A11992-04-08
Other References:
L. EYROLLES ET. AL.: "Retinobenzoic Acids. 6. Retinoid Antagonists with a Heterocyclic Ring", JOURNAL OF MEDICINAL CHEMISTRY, vol. 37, no. 10, 13 May 1994 (1994-05-13), WASHINGTON DC, US, pages 1508-17, XP002024587
H. YOSHIMURA ET. AL.: "A Novel Type of Retinoid Acid Receptor Antagonist. Synthesis and Structure-Activity Relationships of Heterocyclic Ring Containing Benzoic Acid Derivatives.", JOURNAL OF MEDICINAL CHEMISTRY, vol. 38, no. 16, 4 August 1995 (1995-08-04), WASHINGTON DC, US, pages 3163 - 73, XP002024588
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