Title:
SYNTHESIZING METAL NANOPARTICLES ON INDIVIDUAL THIOL-RICH TAGS AS SINGLE-MOLECULE PROBES
Document Type and Number:
WIPO Patent Application WO/2019/024707
Kind Code:
A1
Abstract:
Metal nanoparticles are directly synthesized on polymers comprising a plurality of thiol groups to form compositions useful as electron microscopy tags.
Inventors:
HE WANZHONG (CN)
JIN XIUMEI (CN)
JIN XIUMEI (CN)
Application Number:
PCT/CN2018/096753
Publication Date:
February 07, 2019
Filing Date:
July 24, 2018
Export Citation:
Assignee:
NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN)
International Classes:
C07K19/00; C07F1/12; C12Q1/68; C40B40/10; G01N33/48; G01N33/50
Domestic Patent References:
| WO2007122259A1 | 2007-11-01 | |||
| WO2016118084A1 | 2016-07-28 |
Foreign References:
| CN105801703A | 2016-07-27 | |||
| US20040038264A1 | 2004-02-26 |
Other References:
HE WANZHONG: "Highlighting individual proteins in cellular context by synthesizing gold nanoparticles on clonable EM tags in situ", PROCEEDINGS OF THE FOURTH NATIONAL SYMPOSIUM ON CRYO ELECTRON MICROSCOPY AND STRUCTURAL BIOLOGY, 8 June 2015 (2015-06-08)
LI JIANFANG ET AL.: "Highly selective and sensitive detection of glutathione based on anti- aggregation of gold nanoparticles via pH regulation", SENSORS AND ACTUATORS B: CHEMICAL, vol. 240, 6 September 2016 (2016-09-06), pages 553 - 559, XP029819037
LI JIANFANG ET AL.: "Highly selective and sensitive detection of glutathione based on anti- aggregation of gold nanoparticles via pH regulation", SENSORS AND ACTUATORS B: CHEMICAL, vol. 240, 6 September 2016 (2016-09-06), pages 553 - 559, XP029819037
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