Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
SYNTHETIC ANALOGUES OF PHOSPHATIDYL-MYO-INOSITOL MANNOSIDES WITH AN INHIBITORY ACTIVITY ON THE INFLAMMATORY RESPONSE
Document Type and Number:
WIPO Patent Application WO/2009/153434
Kind Code:
A8
Abstract:
The present invention relates to novel synthetic analogues of phosphatidyl-myo-inositol mannosides (hereinafter referred to as PIMs) of general formula (I): or a pharmaceutically acceptable salt thereof, to the method for preparing same and to the use thereof in the prevention or treatment of a disease associated with the overexpression of cytokines or of chemokines, in particular of TNF and/or of IL‑12. The invention also relates to a pharmaceutical composition comprising at least one synthetic derivative of PIM.

Inventors:
QUESNIAUX RYFFEL VALERIE (FR)
MARTIN OLIVIER (FR)
FRONT SOPHIE (FR)
Application Number:
PCT/FR2009/000595
Publication Date:
February 24, 2011
Filing Date:
May 20, 2009
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
CENTRE NAT RECH SCIENT (FR)
UNIV ORLEANS (FR)
QUESNIAUX RYFFEL VALERIE (FR)
MARTIN OLIVIER (FR)
FRONT SOPHIE (FR)
International Classes:
C07H15/207; A61K31/7034; A61P29/00; A61P31/00; A61P37/00
Attorney, Agent or Firm:
NOVAGRAAF TECHNOLOGIES (Levallois-Perret Cedex, FR)
Download PDF: