Title:
SYNTHETIC C-GLYCOLIPID AND ITS USE FOR TREATING CANCER INFECTIOUS DISEASES AND AUTOIMMUNE DISEASES
Document Type and Number:
WIPO Patent Application WO2003105769
Kind Code:
A3
Abstract:
The invention is directed to compounds of formula (I) wherein X is O, OR NH; R' is a hydrocarbon chain; R<3> and are hydrogen, OH or a monosaccharide; R<5> is hydrogen or a monosaccharide; Q' is optionally present and may be a C1-10 hydrocarbon; X' is optionally present and may be O, S or NR<8>; and Q3 may be a hydrocarbon or hydrogen. The invention is also directed to the use of the compounds for treating cancer, infectious diseases and autoimmune diseases. The invention is also directed to syntheses of the compounds of formula (I).
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Inventors:
TSUJI MORIYA (US)
FRANCK RICHARD W (US)
YANG GUANGLI (US)
CHEN GUANGWU (US)
FRANCK RICHARD W (US)
YANG GUANGLI (US)
CHEN GUANGWU (US)
Application Number:
PCT/US2003/018789
Publication Date:
April 08, 2004
Filing Date:
June 13, 2003
Export Citation:
Assignee:
UNIV NEW YORK (US)
TSUJI MORIYA (US)
FRANCK RICHARD W (US)
YANG GUANGLI (US)
CHEN GUANGWU (US)
TSUJI MORIYA (US)
FRANCK RICHARD W (US)
YANG GUANGLI (US)
CHEN GUANGWU (US)
International Classes:
C07D309/10; A61K31/351; A61K31/70; A61P31/00; A61P31/14; A61P31/18; A61P33/06; A61P35/00; A61P37/06; A61P43/00; C07D407/06; C07H5/06; C07H7/00; C07H15/10; (IPC1-7): A01N43/04; A61K31/70; C07H5/04; C07H5/06; C07H7/06
Foreign References:
| US5780441A | 1998-07-14 | |||
| US5849716A | 1998-12-15 | |||
| US6531453B1 | 2003-03-11 | |||
| US6635622B2 | 2003-10-21 |
Other References:
See also references of EP 1551228A4
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