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Patent Searching and Data


Title:
SYNTHETIC OLIGOSACCHARIDES FOR MORAXELLA VACCINE
Document Type and Number:
WIPO Patent Application WO/2011/137181
Kind Code:
A8
Abstract:
The present invention provides synthetic Moraxella catarrhalis lipooligosaccharide (LOS)-based oligosaccharides and conjugates containing various M. catarrhalis serotype-specific oligosaccharide antigens or various core M. catarrhalis oligosaccharide structures or motifs corresponding to one or more of the three major serotypes and/or members within a given serotype. The oligosaccharides may be synthesized by a chemical assembly methodology relying on a limited number of monosaccharide and disaccharide building blocks. The invention further provides M. catarrhalis LOS-based immunogenic and immunoprotective compositions and antibodies derived therefrom for diagnosing, treating, and preventing infections caused by M. catarrhalis.

Inventors:
CAMPBELL, A., Stewart (4 Sheehan Circle, Framingham, MA, 01701, US)
LOHMAN, Gregory (240 County Road, Ipswich, MA, 01938-2723, US)
PLANTE, Obadiah, J. (12 Roosevelt Avenue, Danvers, MA, 01923, US)
Application Number:
US2011/034172
Publication Date:
February 23, 2012
Filing Date:
April 27, 2011
Export Citation:
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Assignee:
ANCORA PHARMACEUTICALS INC. (200 Boston Avenue, Suite 4975Medford, MA, 02155, US)
CAMPBELL, A., Stewart (4 Sheehan Circle, Framingham, MA, 01701, US)
LOHMAN, Gregory (240 County Road, Ipswich, MA, 01938-2723, US)
PLANTE, Obadiah, J. (12 Roosevelt Avenue, Danvers, MA, 01923, US)
International Classes:
C07H15/04; A61K31/7056; A61P31/04; C07H15/26
Attorney, Agent or Firm:
ELLIOTT, Joshua, T. (Brinks Hofer Gilson & Lione, P.O. Box 110285Research Triangle Park, NC, 27709, US)
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