SYNTHETIC PROCESSES AND INTERMEDIATES FOR PREPARING THERAPEUTIC AZAKETOLIDES

WIPO Patent Application WO/2024/036254

A3

The present invention relates to a process for producing compounds of formula I and/or formula I'. The present invention also relates to a process of selectively cleaving the main ring of a compound of formula IV to provide the starting materials for the synthesis of a compound of formula I or formula I'. The present invention further relates to the intermediates of the processes described herein.

WO2000068385	NOVEL NUCLEIC ACIDS AND PROTEINS WITH GROWTH HORMONE ACTIVITY
WO2008053219	COMPOSITION FOR THE TREATMENT OF GASTROINTESTINAL DISEASES
JP4074645	Compositions and Methods for Inhibiting Tumor Cell Growth

SHI SHUHAO (US)
ZHAO HE (US)
MAO JIANMIN (US)
LI XIBEN (US)
WANG WENYING (US)
ICHIKAWA YOSHITAKA (US)
CLARK ROGER B (US)

PCT/US2023/071989

April 18, 2024

August 10, 2023

Click for automatic bibliography generation  

ZIKANI THERAPEUTICS INC (US)

A61P35/00; A61K31/7052; C07H1/00; C07H15/18; C07H15/26; C07H17/08

US20220177508A1	2022-06-09
EP2287173A1	2011-02-23

QIN YINHUI ET AL: "Design, synthesis and structure-activity relationships of novel N11-, C12- and C13-substituted 15-membered homo-aza-clarithromycin derivatives against various resistant bacteria", BIOORGANIC CHEMISTRY, vol. 113, 1 August 2021 (2021-08-01), US, pages 104992, XP093108972, ISSN: 0045-2068, DOI: 10.1016/j.bioorg.2021.104992
HYOUNG CHEUL KIM ET AL: "Total Synthesis of Azithromycin", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, VERLAG CHEMIE, HOBOKEN, USA, vol. 48, no. 10, 27 January 2009 (2009-01-27), pages 1827 - 1829, XP072079678, ISSN: 1433-7851, DOI: 10.1002/ANIE.200805334

BERVEN, Heidi (US)

View/Download PDF      PDF Help

Previous Patent: APPARATUSES AND METHODS FOR ABLATION TREATMENTS INCLUDING PROBES WITH HANDLE HEATING

Next Patent: SELF POWERING SHAFT