Title:
SYSTEM FOR ANALYZING BIOACTIVE VARIATION USING GENETIC VARIATION INFORMATION ON INDIVIDUAL'S GENOME
Document Type and Number:
WIPO Patent Application WO/2017/116139
Kind Code:
A1
Abstract:
The present invention relates to a system for analyzing and providing bioactive variation information obtained from an individual's genome by comparing a database of multiple whole genomes established by a genome project with the information on the individual's genome which has been input. The present invention comprises: an analysis data input unit for receiving the input of analysis data including information on an individual's genome; a search control unit for comparing bioactive variation information stored in a database with the analysis data, producing analysis results including variation information, included in the analysis data, of a base associated with a protein binding-related amino acid, and generating a result report from the analysis results; and a BAV/biomarker DB in which gene information determining the form of the amino acid in the binding position of various proteins is stored, in order to compare same with the analysis data. The present invention can analyze protein-related genetic features by detecting protein binding amino acid-related variation in an individual's genome by effectively comparing gene variation information stored in the database of a control group with the individual's genome being analyzed.
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Inventors:
JUNG JONGSUN (KR)
Application Number:
PCT/KR2016/015396
Publication Date:
July 06, 2017
Filing Date:
December 28, 2016
Export Citation:
Assignee:
SYNTEKABIO CO LTD (KR)
International Classes:
G16B20/20; G16B25/10; G16B40/00; G16B50/30; G16B20/40
Foreign References:
| KR101117603B1 | 2012-03-07 | |||
| KR20100137398A | 2010-12-30 | |||
| KR20040055893A | 2004-06-30 |
Other References:
LAHTI ET AL.: "Bioinformatics and Variability in Drug Response: a Protein Structural Perspective", JOURNAL OF THE ROYAL SOCIETY INTERFACE, vol. 9, 2012, pages 1409 - 1437, XP055134562
PIRINEN: "Estimating Population Haplotype Frequencies from Pooled SNP Data Using Incomplete Database Information", BIOINFORMATICS, vol. 25, no. 24, 2009, pages 3296 - 3302, XP055395773
PIRINEN: "Estimating Population Haplotype Frequencies from Pooled SNP Data Using Incomplete Database Information", BIOINFORMATICS, vol. 25, no. 24, 2009, pages 3296 - 3302, XP055395773
Attorney, Agent or Firm:
KWON, Hyung Seok (KR)
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