Title:
SYSTEM FOR ANALYZING EXPRESSION PROFILE AND PROGRAM THEREOF
Document Type and Number:
WIPO Patent Application WO/2010/106794
Kind Code:
A1
Abstract:
Provided is a system for analyzing an expression profile whereby a great deal of expression profile data obtained by using a next-generation high-speed sequencer or a similar experimental technique is analyzed at a high speed with a computer commonly employed and thus the gene expression patterns are visualized to thereby easily analyze to what gene a novel gene is similar in function. A system for analyzing an expression profile whereby gene expression profile data is analyzed, which comprises: a memory unit for regarding the count of mRNAs, that have been expressed from a subject gene to be evaluated under each of a plural number of gene expression conditions, as expression data and memorizing the expression data with respect to the name of each subject gene; a correspondence analysis unit for reading out the expression data of each subject gene from the memory unit and conducting correspondence analysis on the basis of the count under each of the expression conditions in the expression data; a coordinate conversion unit for converting n-dimensional scores obtained by the correspondence analysis (wherein n represents a positive integer) into coordinate values for m-dimensionally assigning each gene (wherein m is a positive integer that is less than or equal to n); and an image processing unit for plotting the corresponding coordinate values with respect to each gene and displaying the plot in an image display unit.
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Inventors:
YANO KENTARO (JP)
SHIMIZU AKIFUMI (JP)
SHIMIZU AKIFUMI (JP)
Application Number:
PCT/JP2010/001867
Publication Date:
September 23, 2010
Filing Date:
March 16, 2010
Export Citation:
Assignee:
UNIV MEIJI (JP)
UNIV SHIGA PREFECTURE (JP)
YANO KENTARO (JP)
SHIMIZU AKIFUMI (JP)
UNIV SHIGA PREFECTURE (JP)
YANO KENTARO (JP)
SHIMIZU AKIFUMI (JP)
International Classes:
G06F19/00; G16B45/00
Foreign References:
| JP2005073569A | 2005-03-24 | |||
| JP2009063273A | 2009-03-26 |
Other References:
KENTARO YANO ET AL.: "A new method for gene discovery in large-scale microarray data", NUCLEIC ACIDS RESEARCH, vol. 34, no. 5, 14 March 2006 (2006-03-14), OXFORD, pages 1532 - 1539, XP055103827
EWING ET AL., GENOME RES., vol. 9, 1999, pages 950 - 959
VAN'T VEER, L. J., DAI, H., VAN DE VIJVER, M. J., HE, Y D., HART, A. A., MAO, M., PETERSE, H. L., VAN DER KOOY, K., MARTON, M. J.,: "Gene expression profiling can predict the clinical outcome of breast cancer", NATURE, vol. 415, 2002, pages 530 - 536
NOBORU OHSUMI, L. LEBART ET AL.: "Multivariable Descriptive Analysis Method", 1994, JUSE PRESS LTD.
EWING ET AL., GENOME RES., vol. 9, 1999, pages 950 - 959
VAN'T VEER, L. J., DAI, H., VAN DE VIJVER, M. J., HE, Y D., HART, A. A., MAO, M., PETERSE, H. L., VAN DER KOOY, K., MARTON, M. J.,: "Gene expression profiling can predict the clinical outcome of breast cancer", NATURE, vol. 415, 2002, pages 530 - 536
NOBORU OHSUMI, L. LEBART ET AL.: "Multivariable Descriptive Analysis Method", 1994, JUSE PRESS LTD.
Attorney, Agent or Firm:
SHIGA, Masatake et al. (JP)
Masatake Shiga (JP)
Masatake Shiga (JP)
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