Title:
SYSTEM AND METHOD FOR ESTIMATION OF MISSING DATA IN A MULTIVARIATE LONGITUDINAL SETUP
Document Type and Number:
WIPO Patent Application WO/2013/126724
Kind Code:
A3
Abstract:
A method for estimating values of missing data in partial sets of medical data includes generating a Gaussian mixture with a time-varying mean and time and lag varying covariances. The method generates the estimate for a missing datum with the Gaussian distribution having a selected mean and covariance corresponding to the time of the missing datum. An estimate of the missing datum is generated with reference to the mean of the Gaussian distribution conditioned on other medical data that are observed at the time of the missing datum.
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Inventors:
SRINIVASAN SOUNDARARAJAN (US)
KOHLI PRIYA (US)
KOHLI PRIYA (US)
Application Number:
PCT/US2013/027354
Publication Date:
January 23, 2014
Filing Date:
February 22, 2013
Export Citation:
Assignee:
BOSCH GMBH ROBERT (DE)
SRINIVASAN SOUNDARARAJAN (US)
KOHLI PRIYA (US)
SRINIVASAN SOUNDARARAJAN (US)
KOHLI PRIYA (US)
International Classes:
G06F17/18; G06N5/04; G06Q10/04; G16H10/60; G16H40/67; G16H50/20
Other References:
YANG C YUAN: "Multiple Imputation for Missing Data: Concepts and New Development (Version 9.0)", SUGI PROCEEDINGS, 2000, pages 1 - 13, XP055090353, Retrieved from the Internet [retrieved on 20131126]
FRIEDRICH FAUBEL ET AL: "Bounded conditional mean imputation with Gaussian mixture models: A reconstruction approach to partly occluded features", ACOUSTICS, SPEECH AND SIGNAL PROCESSING, 2009. ICASSP 2009. IEEE INTERNATIONAL CONFERENCE ON, IEEE, PISCATAWAY, NJ, USA, 19 April 2009 (2009-04-19), pages 3869 - 3872, XP031460118, ISBN: 978-1-4244-2353-8
WIKIPEDIA: "Cholesky decomposition", WIKIPEDIA, 21 February 2012 (2012-02-21), XP055090335, Retrieved from the Internet [retrieved on 20131126]
S VAN BUUREN ET AL: "Multiple imputation of missing blood pressure covariates in survival analysis", STATISTICS IN MEDICINE, 30 March 1999 (1999-03-30), ENGLAND, pages 681 - 694, XP055090279, Retrieved from the Internet [retrieved on 20131126], DOI: 10.1002/(SICI)1097-0258(19990330)18:6<681::AID-SIM71>3.3.CO;2-I
TRIVELLOREE RAGHUNATHAN ET AL: "A Multivariate Technique for Multiply Imputing Missing Values Using a Sequence of Regression Models", STATISTICS CANADA, CATALOGUE NO. 12-001, June 2001 (2001-06-01), pages 85 - 95, XP055090349, Retrieved from the Internet [retrieved on 20131126]
FRIEDRICH FAUBEL ET AL: "Bounded conditional mean imputation with Gaussian mixture models: A reconstruction approach to partly occluded features", ACOUSTICS, SPEECH AND SIGNAL PROCESSING, 2009. ICASSP 2009. IEEE INTERNATIONAL CONFERENCE ON, IEEE, PISCATAWAY, NJ, USA, 19 April 2009 (2009-04-19), pages 3869 - 3872, XP031460118, ISBN: 978-1-4244-2353-8
WIKIPEDIA: "Cholesky decomposition", WIKIPEDIA, 21 February 2012 (2012-02-21), XP055090335, Retrieved from the Internet
S VAN BUUREN ET AL: "Multiple imputation of missing blood pressure covariates in survival analysis", STATISTICS IN MEDICINE, 30 March 1999 (1999-03-30), ENGLAND, pages 681 - 694, XP055090279, Retrieved from the Internet
TRIVELLOREE RAGHUNATHAN ET AL: "A Multivariate Technique for Multiply Imputing Missing Values Using a Sequence of Regression Models", STATISTICS CANADA, CATALOGUE NO. 12-001, June 2001 (2001-06-01), pages 85 - 95, XP055090349, Retrieved from the Internet
Attorney, Agent or Firm:
MAGINOT, Paul, J. (Moore & Beck LLPOne Indiana Square, Suite 220, Indianapolis IN, US)
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