Title:
SYSTEM AND METHOD FOR EVALUATION EFFECTS OF ANTIARRHYTHMIC AGENT
Document Type and Number:
WIPO Patent Application WO/2016/111433
Kind Code:
A1
Abstract:
The present invention relates to a system and method for evaluating effects of an antiarrhythmic agent, wherein the system comprises: an action potential measurement part for measuring the cardiac action potential of a patient; an ion channel characteristics determination part for determining ion channel characteristics of the patient using the measured action potential; and an antiarrhythmic agent effect evaluation part for reflecting characteristics of the antiarrhythmic agent on the determined ion channel characteristics of the patient to mock-evaluate therapeutic effects. According to the present invention, the ion channel characteristics can be conveniently determined by measuring the cardiac action potential of the patient, thereby preventing the risk of collecting cardiac cells of the patient, and the therapeutic effects of the antiarrhythmic agent, of which the effect and safety vary significantly depending on the individual ion channel characteristics, can be mock-evaluated even without being directly used for the patient.
Inventors:
PAK HUI NAM (KR)
LEE YOUNG SEON (KR)
LEE YOUNG SEON (KR)
Application Number:
PCT/KR2015/007861
Publication Date:
July 14, 2016
Filing Date:
July 28, 2015
Export Citation:
Assignee:
UNIV YONSEI IACF (KR)
International Classes:
G01N33/15; A61B5/296
Foreign References:
| JP5161963B2 | 2013-03-13 | |||
| JP4565841B2 | 2010-10-20 |
Attorney, Agent or Firm:
YOON, Byong Kuk et al. (KR)
윤병국 (KR)
윤병국 (KR)
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