Title:
SYSTEMS AND METHODS FOR CALIBRATING, CONFIGURING AND VALIDATING AN IMAGING DEVICE OR SYSTEM FOR MULTIPLEX TISSUE ASSAYS
Document Type and Number:
WIPO Patent Application WO/2014/118326
Kind Code:
A3
Abstract:
A system and method for characterization and/or calibration of performance of a multispectral imaging (MSI) system equipping the MSI system for use with a multitude of different fluorescent specimens while being independent on optical characteristics of a specified specimen and providing an integrated system level test for the MSI system. A system and method are adapted to additionally evaluate and express operational parameters performance of the MSI system in terms of standardized units and/or to determine the acceptable detection range of the MSI system.
Inventors:
GARSHA KARL (US)
OTTER MICHAEL (US)
PESTANO GARY ANTHONY (US)
VENTURA FRANK (US)
OTTER MICHAEL (US)
PESTANO GARY ANTHONY (US)
VENTURA FRANK (US)
Application Number:
PCT/EP2014/051920
Publication Date:
December 04, 2014
Filing Date:
January 31, 2014
Export Citation:
Assignee:
VENTANA MED SYST INC (US)
HOFFMANN LA ROCHE (CH)
HOFFMANN LA ROCHE (CH)
International Classes:
G01J3/28; G01J3/10; G01J3/44; G01N21/27; G02B21/36
Domestic Patent References:
| WO2002050518A2 | 2002-06-27 |
Other References:
GARSHA K: "Quantitative Fluorescence Microscopy: Considerations and Controls", 1 January 2008, SPRINGER SERIES ON FLUORESENCE, SPRINGER VERLAG, DE, PAGE(S) 55 - 88, XP007922681
SETH T GAMMON ET AL: "Spectral Unmixing of Multicolored Bioluminescence Emitted from Heterogeneous Biological Sources", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 78, no. 5, 1 March 2006 (2006-03-01), pages 1520 - 1527, XP007922816, ISSN: 0003-2700, [retrieved on 20060131], DOI: 10.1021/AC051999H
GARINI Y ET AL: "Spectral Imaging: Principles and Applications", CYTOMETRY. PART A, JOHN WILEY, HOBOKEN, NJ, US, vol. 69a, 1 August 2006 (2006-08-01), pages 735 - 747, XP002606204, ISSN: 1552-4922, [retrieved on 20060912], DOI: 10.1002/CYTO.A.20311
SETH T GAMMON ET AL: "Spectral Unmixing of Multicolored Bioluminescence Emitted from Heterogeneous Biological Sources", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 78, no. 5, 1 March 2006 (2006-03-01), pages 1520 - 1527, XP007922816, ISSN: 0003-2700, [retrieved on 20060131], DOI: 10.1021/AC051999H
GARINI Y ET AL: "Spectral Imaging: Principles and Applications", CYTOMETRY. PART A, JOHN WILEY, HOBOKEN, NJ, US, vol. 69a, 1 August 2006 (2006-08-01), pages 735 - 747, XP002606204, ISSN: 1552-4922, [retrieved on 20060912], DOI: 10.1002/CYTO.A.20311
Attorney, Agent or Firm:
GOEHRING, Frank et al. (P.O. Box 11 52Nonnenwald 2, Penzberg, DE)
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