Title:
SYSTEMS, METHODS AND COMPUTER PROGRAM PRODUCTS FOR GUIDING THE SELECTION OF THERAPEUTIC TREATMENT REGIMENS
Document Type and Number:
WIPO Patent Application WO2002037398
Kind Code:
A3
Abstract:
Systems, methods and computer program products for guiding selection of a therapeutic treatment regimen or a preventive therapeutic treatment regimen are disclosed. The method comprises (A) providing to a computing device comprising a first knowledge base comprising information about a plurality of different methylation statuses at selected sites of the DNA in cells with a known disease or medical condition and/or healthy cells, a second knowledge base comprising a plurality of expert rules for evaluating and selecting a type of disease or medical condition based on the methylation status at selected sites of the DNA of a patient, (B) generating in said computing device a ranked listing of diseases or medical conditions based on the information about the methylation status at selected sites of the DNA of the patient, the first knowledge base and the second knowledge base.
Inventors:
BERLIN KURT (DE)
OLEK ALEXANDER (DE)
PIEPENBROCK CHRISTIAN (DE)
OLEK ALEXANDER (DE)
PIEPENBROCK CHRISTIAN (DE)
Application Number:
PCT/EP2001/012666
Publication Date:
August 21, 2003
Filing Date:
November 02, 2001
Export Citation:
Assignee:
EPIGENOMICS AG (DE)
BERLIN KURT (DE)
OLEK ALEXANDER (DE)
PIEPENBROCK CHRISTIAN (DE)
BERLIN KURT (DE)
OLEK ALEXANDER (DE)
PIEPENBROCK CHRISTIAN (DE)
International Classes:
C12N15/09; G06F19/00; G06Q50/00; G16B40/00; (IPC1-7): G06F19/00
Domestic Patent References:
| WO2000044934A2 | 2000-08-03 |
Foreign References:
| US6081786A | 2000-06-27 | |||
| EP1176539A1 | 2002-01-30 | |||
| US5985559A | 1999-11-16 | |||
| EP0976835A1 | 2000-02-02 |
Other References:
LATHORP R H ET AL: "KNOWLEDGE-BASED AVOIDANCE OF DRUG-RESISTANT HIV MUTANTS", AI MAGAZINE, LA CANADA, CA, vol. 20, no. 1, March 1999 (1999-03-01), pages 13 - 25, XP000972629, ISSN: 0738-4602
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