Title:
SYSTEMS AND METHODS FOR RAPIDLY SCREENING SAMPLES BY MASS SPECTROMETRY
Document Type and Number:
WIPO Patent Application WO/2012/063108
Kind Code:
A3
Abstract:
Systems and methods are used to rapidly screening samples. A fast sample introduction device that is non-chromatographic is instructed to supply each sample of a plurality samples to a tandem mass spectrometer using a processor. The fast sample introduction device can include a flow injection analysis device, an ion mobility analysis device, or a rapid sample cleanup device. The tandem mass spectrometer is instructed to perform fragmentation scans at two or more mass selection windows across a mass range of each sample of the plurality of samples using the processor. The two or more mass selection windows across the mass range can have fixed or variable window widths. The tandem mass spectrometer can be instructed to obtain a mass spectrum of the mass range before instructing the tandem mass spectrometer to perform the fragmentation scans.
Inventors:
BONNER RONALD (CA)
TATE STEPHEN A (CA)
TATE STEPHEN A (CA)
Application Number:
PCT/IB2011/002594
Publication Date:
July 19, 2012
Filing Date:
November 02, 2011
Export Citation:
Assignee:
DH TECHNOLOGIES DEV PTE LTD (SG)
BONNER RONALD (CA)
TATE STEPHEN A (CA)
BONNER RONALD (CA)
TATE STEPHEN A (CA)
International Classes:
H01J49/00
Other References:
J. THROCK WATSON, O. DAVID SPARKMAN: "Introduction to Mass Spectrometry", 2007, JOHN WILEY & SONS LTD, Chichester, West Sussex, England, ISBN: 978-0-470-51634-8, XP002674736
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