Title:
T CELL EVALUATION METHOD AND COMPOSITION FOR T CELL EVALUATION
Document Type and Number:
WIPO Patent Application WO/2023/074711
Kind Code:
A1
Abstract:
A T cell evaluation method that comprises a detection step for detecting the expression of at least one gene selected from the group consisting of the following genes (I) to (III) in T cells, and an evaluation step for evaluating the qualities of the T cells with the use of the expression of the gene as an indicator. (I) A gene encoding a polypeptide containing an amino acid sequence represented by any one of SEQ ID NOS: 1-77. (II) A gene encoding a polypeptide containing an amino acid sequence in which one or more amino acid residues are substituted, deleted, inserted and/or added in an amino acid sequence represented by any one of SEQ ID NOS: 1-77. (III) A gene encoding a polypeptide containing an amino acid sequence having 70% or more identity with an amino acid sequence represented by any one of SEQ ID NOS: 1-77.
Inventors:
KANEKO SHIN (JP)
KAWAI YOHEI (JP)
YAMAGUCHI KANA (JP)
KUMAKI YUICHI (JP)
FUTAMI TORU (JP)
KAWAI YOHEI (JP)
YAMAGUCHI KANA (JP)
KUMAKI YUICHI (JP)
FUTAMI TORU (JP)
Application Number:
PCT/JP2022/039806
Publication Date:
May 04, 2023
Filing Date:
October 26, 2022
Export Citation:
Assignee:
UNIV KYOTO (JP)
International Classes:
C12N15/12; C07K16/18; C12M1/00; C12M1/34; C12N5/0783; C12N15/115; C12N15/13; C12Q1/02; C12Q1/6813; G01N33/53
Foreign References:
| JP2021501318A | 2021-01-14 | |||
| US20170233808A1 | 2017-08-17 | |||
| JP2019154320A | 2019-09-19 |
Other References:
GEORGE ELIAS; BENSON OGUNJIMI; VIGGO VAN TENDELOO: "Tracking Dye‐Independent Approach to Identify and Isolate In Vitro Expanded T Cells", CYTOMETRY A, WILEY-LISS, HOBOKEN, USA, vol. 95, no. 10, 29 July 2019 (2019-07-29), Hoboken, USA, pages 1096 - 1107, XP072332516, ISSN: 1552-4922, DOI: 10.1002/cyto.a.23867
Attorney, Agent or Firm:
SHA PATENT AND TRADEMARK FIRM (JP)
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