Title:
TABLET
Document Type and Number:
WIPO Patent Application WO/2017/018473
Kind Code:
A1
Abstract:
The present invention provides a tablet in which the stability of active ingredients (a potassium ion-competitive acid blocker and acetylsalicylic acid) is high and the pharmacological activities of the active ingredients can be exerted stably and rapidly after the administration of the tablet.
The present invention relates to an enteric coated tablet having an inner core and an outer layer, wherein the inner core contains acetylsalicylic acid and the outer layer contains a potassium ion-competitive acid blocker that is not enterically coated.
Inventors:
MAEDA ARISA (JP)
SUGIYAMA YUICHI (JP)
UCHIYAMA YOSHIHIRO (JP)
SUGIYAMA YUICHI (JP)
UCHIYAMA YOSHIHIRO (JP)
Application Number:
PCT/JP2016/072109
Publication Date:
February 02, 2017
Filing Date:
July 28, 2016
Export Citation:
Assignee:
TAKEDA PHARMACEUTICALS CO (JP)
International Classes:
A61K31/616; A61K9/30; A61K31/4439; A61K47/12; A61K47/32; A61K47/38; A61P1/04; A61P7/02; A61P9/00; A61P9/12; A61P29/00
Foreign References:
| JP2014533656A | 2014-12-15 | |||
| JP2004536809A | 2004-12-09 | |||
| US20100305163A1 | 2010-12-02 |
Other References:
YOSHIKAZU KINOSHITA ET AL.: "PPI Chiryo no Kadai to Tenbo", CLINICS IN GASTROENTEROLOGY, vol. 18, no. 3, 10 June 2015 (2015-06-10), pages 237 - 241, XP009508666
EMIKO IIDA ET AL.: "Kalium Ion Kyogogata Acid Blocker -Proton Pump Inhibitor- Vonoprazan Fumarate-Jo (Takecab® Tablets 10mg·20mg", JOURNAL OF JAPANESE SOCIETY OF HOSPITAL PHARMACISTS, vol. 51, no. 6, 1 June 2015 (2015-06-01), pages 770 - 772, XP009508538
See also references of EP 3329921A4
EMIKO IIDA ET AL.: "Kalium Ion Kyogogata Acid Blocker -Proton Pump Inhibitor- Vonoprazan Fumarate-Jo (Takecab® Tablets 10mg·20mg", JOURNAL OF JAPANESE SOCIETY OF HOSPITAL PHARMACISTS, vol. 51, no. 6, 1 June 2015 (2015-06-01), pages 770 - 772, XP009508538
See also references of EP 3329921A4
Attorney, Agent or Firm:
TAKASHIMA, Hajime (JP)
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