TABLETS AND PROCESS FOR PRODUCING TABLETS

Title:

TABLETS AND PROCESS FOR PRODUCING TABLETS

Document Type and Number:

WIPO Patent Application WO/2000/048575

Kind Code:

A1

Abstract:

Tablets obtained by binding a powdery mixture (5a, 5) containing at least the principal agent (2), a highly wettable saccharide (3) and a disintegrating agent (4) by using a binder (6, 6c) containing a highly wettable saccharide to give granules (1a, 1b, 1c), and then compression-molding these granules (1a, 1b, 1c). A process for producing tablets which comprises the step of mixing a powdery mixture (5a, 5), which has been prepared by homogeneously mixing at least the principal agent (2), highly wettable saccharide grains (3) and disintegrating agent grains (4), with air to give a fluidized bed; the step of producing granules (1a, 1b, 1c) containing the principal agent by spraying an aqueous solution of a binder (6, 6c) and a highly wettable saccharide (3) dissolved therein onto the above-mentioned fluidized bed of the powdery mixture (5, 5a) followed by spraying; and the step of compression-molding these granules (1a, 1b, 1c) containing the principal agent (2).

Inventors:

WATANABE YASUSHI (JP)
MORIMOTO KIYOSHI (JP)
IWASE YUJI (JP)
HIRUTA SATORU (JP)

Application Number:

PCT/JP2000/000870

Publication Date:

August 24, 2000

Filing Date:

February 16, 2000

Export Citation:

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Assignee:

KYOWA HAKKO KOGYO KK (JP)
WATANABE YASUSHI (JP)
MORIMOTO KIYOSHI (JP)
IWASE YUJI (JP)
HIRUTA SATORU (JP)

International Classes:

A61K9/00; A61K9/20; (IPC1-7): A61K9/20; A61K47/26

Foreign References:

EP0553777A2	1993-08-04
EP0745382A1	1996-12-04
JPH1112161A	1999-01-19
JPH11263723A	1999-09-28

Other References: