TANDEM MASS SPECTROMETRY DEVICE AND PROGRAM FOR SAME DEVICE

WIPO Patent Application WO/2018/163926

A1

In this invention, when data is obtained by mass spectrometry, a mass spectrum analysis unit (32) immediately determines the integration value of signal intensities on the mass spectrum for each m/z sub-range of a predetermined m/z-width into which the entire m/z range for the substance being measured is divided. Then, the mass spectrum analysis unit (32) selects only the m/z sub-ranges which have signal intensity integration values equal to or greater than a predetermined threshold value for MS/MS analysis. For each of the m/z sub-ranges selected, the MS/MS analysis is executed by an MS/MS analysis control unit (41), taking as a precursor ion an ion whereof the m/z is included within the m/z sub-range. After executing repeatedly a measurement cycle containing one iteration of mass spectrometry and one or a plurality of iterations of MS/MS analysis in this manner, an identification processing unit (35) sorts out the ions derived from an identical component on the basis of the peak retention times in an extracted-ion chromatogram of each product ion, and identifies the component. In this manner, while collecting information on a product ion derived from an ion observed in the mass spectrum as thoroughly as possible, the number of MS/MS analyses executed can be reduced, thereby shortening the time for one measurement cycle.

TOYAMA ATSUHIKO (JP)
YAMAMOTO HIDEKI (JP)

PCT/JP2018/007423

September 13, 2018

February 28, 2018

Click for automatic bibliography generation  

SHIMADZU CORP (JP)

H01J49/40; G01N27/62

WO2015107642A1

2015-07-23

JP2013537312A	2013-09-30
JP2007527992A	2007-10-04
JP2004259452A	2004-09-16

KYOTO INTERNATIONAL PATENT LAW OFFICE (JP)

View/Download PDF      PDF Help

Previous Patent: LEVELING FOUR-LEGGED STEP LADDER

Next Patent: ABNORMALITY DIAGNOSIS DEVICE AND ABNORMALITY DIAGNOSIS METHOD FOR BOOSTER DEVICE