Title:
TARGET FOR TREATING HEPATITIS B VIRUS
Document Type and Number:
WIPO Patent Application WO/2016/201605
Kind Code:
A1
Abstract:
The present invention discloses a target for treating a Hepatitis B virus, and a use of the target in preparing a drug for treating the Hepatitis B virus. AKT and mTOR proteins as novel targets in an anti-HBV treatment have an improved anti-viral effect compared to the nucleoside analogue drug Tenofovir, and can reduce and clear HBV cccDNA, addressing the problem in which current antiviral drugs are unable to clear Hepatitis B cccDNA and relapse easily occurs; the invention thus has good prospects of wide medical application.
Inventors:
YONG LIAO (CN)
DI MOU (CN)
DI MOU (CN)
Application Number:
PCT/CN2015/081467
Publication Date:
December 22, 2016
Filing Date:
June 15, 2015
Export Citation:
Assignee:
YONG LIAO (CN)
International Classes:
C07K14/47; A61K31/365; A61K31/436; A61K38/17; A61P31/20
Foreign References:
| CN101466683A | 2009-06-24 | |||
| CN103732226A | 2014-04-16 |
Other References:
WU, XIANGQIN: "Phosphorylation Akt Regulate Autophagy and the C77 of Fungi Secondary Metabolites Affect Autophagy and HBV Replication", MASTER'S DISSERTATION OF ANHUI UNIVERSITY, 31 December 2014 (2014-12-31)
Attorney, Agent or Firm:
LAW OFFICE OF CHONGQING UNIVERSITY (CN)
重庆大学专利中心 (CN)
重庆大学专利中心 (CN)
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