TARGETED DENDRIMER-DRUG CONJUGATES

Title:

TARGETED DENDRIMER-DRUG CONJUGATES

Document Type and Number:

WIPO Patent Application WO/2011/072290

Kind Code:

A3

Abstract:

V The invention provides for dendrimer conjugates useful for liver- specific delivery of therapeutic agents. The therapeutic agent is associated to the dendrimer through a enzyme-cleavable covalent linkage.

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WO/1998/039037	CONCURRENT IN-VIVO IMMUNOCONJUGATE BINDING TO MULTIPLE EPITOPES OF VASCULAR PERMEABILITY FACTOR ON TUMOR-ASSOCIATED BLOOD VESSELS
WO/1993/024476	WATER-SOLUBLE POLYMERIC CARRIERS FOR DRUG DELIVERY
WO/1992/017210	NOVEL PROTEIN POLYCATION CONJUGATES

Inventors:

EL-SAYED MOHAMED E H (US)
ENSMINGER WILLIAM (US)
SHEWACH DONNA (US)

Application Number:

PCT/US2010/060093

Publication Date:

November 17, 2011

Filing Date:

December 13, 2010

Export Citation:

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Assignee:

UNIV MICHIGAN (US)
EL-SAYED MOHAMED E H (US)
ENSMINGER WILLIAM (US)
SHEWACH DONNA (US)

International Classes:

A61K47/48; A61K31/74; A61P35/00; C08G83/00

Foreign References:

US20050153913A1	2005-07-14
US20070060499A1	2007-03-15
US20040228831A1	2004-11-18

Attorney, Agent or Firm:

HONG, Julie, J. et al. (Gerstein & Borun LLP233 S. Wacker Drive,6300 Willis Towe, Chicago IL, US)

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