Title:
TEBUCONAZOLE POLYMORPH AND PREPARATION METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2019/095891
Kind Code:
A1
Abstract:
The present invention provides a tebuconazole polymorph and a preparation method therefor. In particular, the present invention relates to a polymorph of (RS)-1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol, a preparation method therefor and use thereof. The tebuconazole polymorph of the present invention has a high purity and excellent crystallization properties, is stable under high humidity, high temperature and light conditions, has excellent solubility, and has high processing properties for formulations, high biological activities and good sterilization effects. The preparation method is simple, has stable processes, and can be implemented on a large scale. The polymorph can greatly improve the quality control and industrial application of tebuconazole-containing pesticides.
Inventors:
LI ZHONG (CN)
REN GUOBIN (CN)
XU XIAOYONG (CN)
QI MINGHUI (CN)
HU JIAN (CN)
GONG CHENGYU (CN)
REN GUOBIN (CN)
XU XIAOYONG (CN)
QI MINGHUI (CN)
HU JIAN (CN)
GONG CHENGYU (CN)
Application Number:
PCT/CN2018/109675
Publication Date:
May 23, 2019
Filing Date:
October 10, 2018
Export Citation:
Assignee:
UNIV EAST CHINA SCIENCE & TECH (CN)
International Classes:
C07D249/08
Foreign References:
| CN101130522A | 2008-02-27 | |||
| CN102432556A | 2012-05-02 | |||
| DE3733755A1 | 1989-04-20 | |||
| DE3733755A1 | 1989-04-20 |
Other References:
J W MULLENS: "Crystallization", 1993, BUTTERWORTH-HEINEMAN LTD.
See also references of EP 3712136A4
See also references of EP 3712136A4
Attorney, Agent or Firm:
XU AND PARTNERS, LLC. (CN)
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