Title:
TECHNETIUM-99M COMPLEXES FOR USE AS RADIOPHARMACEUTICALS
Document Type and Number:
WIPO Patent Application WO1992007860
Kind Code:
A3
Abstract:
The present invention relates to novel technetium-99m complexes and to methods of preparing the complexes. The present invention further relates to a radiopharmaceutical compositions comprising the complexes, to the use of the compositions for examining the renal function, and to a kit for preparing such compositions.
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Inventors:
NOSCO DENNIS L (US)
Application Number:
PCT/US1991/007908
Publication Date:
September 03, 1992
Filing Date:
October 25, 1991
Export Citation:
Assignee:
MALLINCKRODT MEDICAL INC (US)
International Classes:
A61K51/04; C07C49/92; C07C239/08; C07C337/08; C07F13/00; A61K51/00; (IPC1-7): C07F13/00; C07C239/16; C07C239/20; C07C337/08; C07C59/00
Domestic Patent References:
| WO1990005733A1 | 1990-05-31 |
Foreign References:
| EP0250013A1 | 1987-12-23 | |||
| EP0194843A2 | 1986-09-17 | |||
| EP0123504A2 | 1984-10-31 | |||
| EP0273452A2 | 1988-07-06 | |||
| EP0306168A1 | 1989-03-08 | |||
| EP0024464A1 | 1981-03-11 | |||
| EP0074429A1 | 1983-03-23 | |||
| US4113850A | 1978-09-12 |
Other References:
Chemical Abstracts, volume 91, no. 12, 17 September 1979, (Columbus, Ohio, US), Mazzi, Ulderico et al : "Pentane-2,4-dione complexes of technetium-99 ", see page 669, abstract 101279g, & Transition Met. Chem. 1979, 4( 3), 151- 15
Chemical Abstracts, volume 96, no. 16, 19 April 1982, (Columbus, Ohio, US), Sekine, Tsutomu et al : "Radiochemical synthesis of new acetylacetone complexes of technetium and their properties ", see page 606, abstract 131701j, & Radiochim.Acta 1981, 29(20), 139- 14
Chemical Abstracts, volume 111, no. 5, 31 July 1989, (Columbus, Ohio, US), Packard, A.B. et al : "Synthesis and biological properties of the lipophilic technetium-99m complex 99mTc(acac)3. ", see page 295, abstract 35930r, & Nucl.Med.Biol. 1989, 16( 3), 291- 29
Chemical Abstracts, volume 96, no. 16, 19 April 1982, (Columbus, Ohio, US), Sekine, Tsutomu et al : "Radiochemical synthesis of new acetylacetone complexes of technetium and their properties ", see page 606, abstract 131701j, & Radiochim.Acta 1981, 29(20), 139- 14
Chemical Abstracts, volume 111, no. 5, 31 July 1989, (Columbus, Ohio, US), Packard, A.B. et al : "Synthesis and biological properties of the lipophilic technetium-99m complex 99mTc(acac)3. ", see page 295, abstract 35930r, & Nucl.Med.Biol. 1989, 16( 3), 291- 29
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