Title:
TEST KIT FOR DETECTING CANCERS
Document Type and Number:
WIPO Patent Application WO/2008/067777
Kind Code:
A1
Abstract:
A test kit for detecting activities of arylsulphatases or isoenzymes thereof, comprises
4-methyl umbelliferyl sulfate and 4-methyl umbelliferone. The test kit can
be used for screening early cancers, monitoring therapeutic effectiveness and
cancer recurrence.
Inventors:
XU JUNPU (CN)
CHEN ZHAO (CN)
ZHOU HAIMENG (CN)
DAI JIE (CN)
HE BIAO (CN)
CHEN ZHAO (CN)
ZHOU HAIMENG (CN)
DAI JIE (CN)
HE BIAO (CN)
Application Number:
PCT/CN2008/000081
Publication Date:
June 12, 2008
Filing Date:
January 11, 2008
Export Citation:
Assignee:
BEIJING ACCB BIOTECH LTD (CN)
XU JUNPU (CN)
CHEN ZHAO (CN)
ZHOU HAIMENG (CN)
DAI JIE (CN)
HE BIAO (CN)
XU JUNPU (CN)
CHEN ZHAO (CN)
ZHOU HAIMENG (CN)
DAI JIE (CN)
HE BIAO (CN)
International Classes:
C12Q1/44; G01N33/573
Foreign References:
| JP2004305008A | 2004-11-04 |
Other References:
CHRISTOMANOU H. ET AL.: "A sensitive fluorescence assay for the simultaneous and separate determination of arylsulphatases A and B", CLINICA CHIMIC ACTA, vol. 79, no. 3, 1977, pages 527 - 531, XP025200640
MERCELIS R. ET AL.: "Arylsulphatases A and B in human diploid fibroblasts: differential assay with 4-methylumbelliferylsulphate and AgNO3", CLINICA CHIMIC ACTA, vol. 93, 1979, pages 85 - 92, XP025217850
WANG M. ET AL.: "Observation of arylsulfates activities in urines of patients suffering from blood disease", JOURNAL OF BENGBU MEDICAL COLLEGE, vol. 18, no. 1, 1993, pages 56 - 57, XP008131832
CHEN T. ET AL.: "Clinical application of detecting activities of arylsulphatase B in morning urines", JOURNAL OF CLINICAL LABORATORY SCIENCE, vol. 14, no. 1, 1996, pages 24 - 25
CHEN T. ET AL.: "Separation of arylsulphatases in urines by a precipitation method and detection of activities thereof", JOURNAL OF CLINICAL LABORATORY SCIENCE, vol. 13, no. 4, 1995, pages 174 - 175
See also references of EP 2085483A4
WOZNIAK, A. ET AL., NEOPLASMA, vol. 49, no. 1, 2002, pages 10 - 5
GASA, S. ET AL., CANCER RES, vol. 40, no. 10, 1980, pages 3804 - 9
ROZWODOWSKA, M. ET AL., POL MERKURIUSZ LEK, vol. 17, no. 99, 2004, pages 252 - 4
CHETRITE, G.S. ET AL., ANTICANCER RES, vol. 25, no. 4, 2005, pages 2827 - 30
DZIALOSZYNSKI, L.M. ET AL., CLIN. CHIM. ACTA, vol. 14, no. 4, 1966, pages 450 - 3
UCHIMURA, K. ET AL., METHODS IN ENZYMOLOGY, vol. 416, 2006, pages 243
SHERMAN, W.R. ET AL., BIOCHEM J., vol. 102, 1967, pages 905
MERCELIS R. ET AL.: "Arylsulphatases A and B in human diploid fibroblasts: differential assay with 4-methylumbelliferylsulphate and AgNO3", CLINICA CHIMIC ACTA, vol. 93, 1979, pages 85 - 92, XP025217850
WANG M. ET AL.: "Observation of arylsulfates activities in urines of patients suffering from blood disease", JOURNAL OF BENGBU MEDICAL COLLEGE, vol. 18, no. 1, 1993, pages 56 - 57, XP008131832
CHEN T. ET AL.: "Clinical application of detecting activities of arylsulphatase B in morning urines", JOURNAL OF CLINICAL LABORATORY SCIENCE, vol. 14, no. 1, 1996, pages 24 - 25
CHEN T. ET AL.: "Separation of arylsulphatases in urines by a precipitation method and detection of activities thereof", JOURNAL OF CLINICAL LABORATORY SCIENCE, vol. 13, no. 4, 1995, pages 174 - 175
See also references of EP 2085483A4
WOZNIAK, A. ET AL., NEOPLASMA, vol. 49, no. 1, 2002, pages 10 - 5
GASA, S. ET AL., CANCER RES, vol. 40, no. 10, 1980, pages 3804 - 9
ROZWODOWSKA, M. ET AL., POL MERKURIUSZ LEK, vol. 17, no. 99, 2004, pages 252 - 4
CHETRITE, G.S. ET AL., ANTICANCER RES, vol. 25, no. 4, 2005, pages 2827 - 30
DZIALOSZYNSKI, L.M. ET AL., CLIN. CHIM. ACTA, vol. 14, no. 4, 1966, pages 450 - 3
UCHIMURA, K. ET AL., METHODS IN ENZYMOLOGY, vol. 416, 2006, pages 243
SHERMAN, W.R. ET AL., BIOCHEM J., vol. 102, 1967, pages 905
Attorney, Agent or Firm:
BEI & OCEAN (Ste. 603West Anshan Road,Nankai District, Tianjin 3, CN)
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