Title:
TESTING SUPPORT DEVICE
Document Type and Number:
WIPO Patent Application WO/2023/176532
Kind Code:
A1
Abstract:
The testing support device comprises a communicator and a processor. The communicator receives amplification date for testing that shows the degree of amplification of a first gene derived from a virus or a bacterium to be tested and the degree of amplification of a second gene derived from a subject, obtained by subjecting a sample to PCR. The processor determines a score that shows the degree to which the amplification data for testing deviate from standard amplification data using a model constructed by machine learning a plurality of amplification data for learning, and outputs the score.
Inventors:
TSUCHIYA HAYATO
YAMAGUCHI JUN
YAMAGUCHI JUN
Application Number:
PCT/JP2023/008212
Publication Date:
September 21, 2023
Filing Date:
March 06, 2023
Export Citation:
Assignee:
KAWASAKI HEAVY IND LTD (JP)
International Classes:
C12Q1/686; C12M1/00; C12M1/34
Foreign References:
| JP2021007351A | 2021-01-28 | |||
| JP2020115777A | 2020-08-06 | |||
| JP2018523998A | 2018-08-30 |
Other References:
BURDUKIEWICZ MICHAł, SPIESS ANDREJ-NIKOLAI, BLAGODATSKIKH KONSTANTIN A., LEHMANN WERNER, SCHIERACK PETER, RöDIGER STEFAN: "Algorithms for automated detection of hook effect-bearing amplification curves", BIOMOLECULAR DETECTION AND QUANTIFICATION, vol. 16, 1 December 2018 (2018-12-01), pages 1 - 4, XP055828223, ISSN: 2214-7535, DOI: 10.1016/j.bdq.2018.08.001
ANONYMOUS: "qPCR troubleshooting: interpreting amplification curves and diagnosing problems", BIOSEARCH TECHNOLOGIES, 18 August 2021 (2021-08-18), XP093092759, Retrieved from the Internet [retrieved on 20231018]
MLO STAFF: "Interpretation of qPCR curve shapes", MLO - MEDICAL LABORATORY OBSERVER, 18 June 2015 (2015-06-18), pages 1 - 8, XP093092763, Retrieved from the Internet [retrieved on 20231018]
ANONYMOUS: "Fehlerbehebung in der RT-PCR/ RT-qPCR ", MERCK, 30 December 2020 (2020-12-30), pages 1 - 39, XP093092764, Retrieved from the Internet [retrieved on 20231018]
ANONYMOUS: "qPCR troubleshooting: interpreting amplification curves and diagnosing problems", BIOSEARCH TECHNOLOGIES, 18 August 2021 (2021-08-18), XP093092759, Retrieved from the Internet
MLO STAFF: "Interpretation of qPCR curve shapes", MLO - MEDICAL LABORATORY OBSERVER, 18 June 2015 (2015-06-18), pages 1 - 8, XP093092763, Retrieved from the Internet
ANONYMOUS: "Fehlerbehebung in der RT-PCR/ RT-qPCR ", MERCK, 30 December 2020 (2020-12-30), pages 1 - 39, XP093092764, Retrieved from the Internet
Attorney, Agent or Firm:
KATSURAGAWA, Naoki (JP)
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