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Title:
TETRACYCLIC ARYLSULFONYL INDOLES HAVING SEROTONIN RECEPTOR AFFINITY
Document Type and Number:
WIPO Patent Application WO2004000849
Kind Code:
A3
Abstract:
The present invention relates to novel tetracyclic arylsulfonyl indoles according to General Formula (I), their derivatives, their analogues, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates, novel intermediates described herein and pharmaceutically acceptable compositions containing them. This invention particularly relates to novel tetracyclic arylsulfonyl indoles of the general formula (I), their derivatives, their analogues, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, their pharmaceutically acceptable solvates, novel intermediates described herein and pharmaceutically acceptable compositions containing them. This invention also relates to process/es for preparing such compound/s of general formula (I), composition/s containing effective amount/s of such a compound and the use of such a compound/composition in therapy.

Inventors:
JASTI VENKATESWARLU (IN)
RAMAKRISHNA VENKATA SATYA NIRO (IN)
KAMBHAMPATI RAMA SASTRI (IN)
BATTULA SRINIVASA REDDY (IN)
VEERARAEDDY ARAVA (IN)
RAO VENKATA SATYA VEERABHADRA (IN)
Application Number:
PCT/IN2003/000222
Publication Date:
March 25, 2004
Filing Date:
June 19, 2003
Export Citation:
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Assignee:
SUVEN LIFE SCIENCES LTD (IN)
JASTI VENKATESWARLU (IN)
RAMAKRISHNA VENKATA SATYA NIRO (IN)
KAMBHAMPATI RAMA SASTRI (IN)
BATTULA SRINIVASA REDDY (IN)
VEERARAEDDY ARAVA (IN)
RAO VENKATA SATYA VEERABHADRA (IN)
International Classes:
C07D513/04; A61K9/02; A61K9/08; A61K9/10; A61K9/14; A61K9/20; A61K9/48; A61K31/425; A61K31/429; A61K31/4453; A61K31/496; A61K31/5377; A61K45/00; A61P1/04; A61P1/08; A61P3/04; A61P25/00; A61P25/06; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P25/30; A61P43/00; C07D498/04; (IPC1-7): C07D513/04; A61K31/429; A61P25/00
Domestic Patent References:
WO2000034242A12000-06-15
Foreign References:
GB2341549A2000-03-22
US3481953A1969-12-02
Other References:
RUSSELL M G N ET AL: "N-Arylsulfonylindole derivatives as serotonin 5 - HT6 receptor ligands", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. WASHINGTON, US, vol. 44, no. 23, 8 November 2001 (2001-11-08), pages 3881 - 3895, XP002234833, ISSN: 0022-2623
PATENT ABSTRACTS OF JAPAN vol. 2000, no. 04 31 August 2000 (2000-08-31)
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