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Title:
TETRACYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2021/023154
Kind Code:
A1
Abstract:
Disclosed are a compound as shown in formula (I), an optical isomer thereof and a pharmaceutically acceptable salt thereof, and the use of the compound as a KRAS inhibitor.

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Inventors:
GUO SHUCHUN (CN)
FAN JUN (CN)
LIU YANG (CN)
PENG JIANBIAO (CN)
GUO HAIBING (CN)
Application Number:
PCT/CN2020/106573
Publication Date:
February 11, 2021
Filing Date:
August 03, 2020
Export Citation:
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Assignee:
SHANGHAI JEMINCARE PHARMACEUTICALS CO LTD (CN)
JIANGXI JEMINCARE GROUP CO LTD (CN)
International Classes:
A61K31/519; C07D498/14; A61P35/00; C07D498/22
Domestic Patent References:
WO2018206539A12018-11-15
WO2019051291A12019-03-14
WO2018119183A22018-06-28
WO2018217651A12018-11-29
WO2019099524A12019-05-23
Foreign References:
CN201910712388A2019-08-02
CN201910899724A2019-09-23
CN201911157922A2019-11-22
CN202010054185A2020-01-17
Other References:
See also references of EP 4011886A4
Attorney, Agent or Firm:
SHANGHAI BESHINING LAW OFFICE (CN)
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