Title:
TETRACYCLIC DERIVATIVES AS KRAS INHIBITORS
Document Type and Number:
WIPO Patent Application WO/2024/051721
Kind Code:
A1
Abstract:
The present disclosure provides certain tetracyclic derivatives that inhibit certain K-Ras proteins and are therefore useful for the treatment of cancers mediated by such proteins. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
Inventors:
FU JIPING (US)
SUN YONGFENG (CN)
SUN YONGFENG (CN)
Application Number:
PCT/CN2023/117149
Publication Date:
March 14, 2024
Filing Date:
September 06, 2023
Export Citation:
Assignee:
NIKANG THERAPEUTICS INC (US)
SHANGHAI BLUERAY BIOPHARMA CO LTD (CN)
SHANGHAI BLUERAY BIOPHARMA CO LTD (CN)
International Classes:
C07D498/14; A61K31/517; A61K31/519; A61P35/00; C07D498/16; C07D498/18; C07D498/22; C07D519/00
Domestic Patent References:
| WO2023001141A1 | 2023-01-26 | |||
| WO2023284730A1 | 2023-01-19 | |||
| WO2023030385A1 | 2023-03-09 | |||
| WO2022173678A1 | 2022-08-18 | |||
| WO2022042630A1 | 2022-03-03 |
Foreign References:
| CN110603258A | 2019-12-20 | |||
| CN114980976A | 2022-08-30 |
Attorney, Agent or Firm:
CHINA PATENT AGENT (H.K.) LTD. (CN)
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