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Title:
TETRACYCLINE COMPOUNDS
Document Type and Number:
WIPO Patent Application WO/2011/025982
Kind Code:
A3
Abstract:
The present invention is directed to a compound represented by Structural Formula (1): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (I) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (I) and its therapeutic use.

Inventors:
DENG YONGHONG (US)
PLAMONDON LOUIS (US)
SUN CUIXIANG (US)
XIAO XIAO-YI (US)
ZHOU JINGYE (US)
SUTCLIFFE JOYCE A (US)
RONN MAGNUS P (US)
Application Number:
PCT/US2010/047035
Publication Date:
September 22, 2011
Filing Date:
August 27, 2010
Export Citation:
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Assignee:
TETRAPHASE PHARMACEUTICALS INC (US)
DENG YONGHONG (US)
PLAMONDON LOUIS (US)
SUN CUIXIANG (US)
XIAO XIAO-YI (US)
ZHOU JINGYE (US)
SUTCLIFFE JOYCE A (US)
RONN MAGNUS P (US)
International Classes:
A61K31/165; C07C237/26; A61K31/18; A61K31/397; A61K31/401; A61K31/4164; A61K31/4453; A61P31/04; C07C311/21; C07D207/04; C07D211/54; C07D213/82; C07D233/60; C07D295/088; C07D307/10
Domestic Patent References:
WO2007133798A22007-11-22
Other References:
ABBANAT D ET AL: "New agents in development for the treatment of bacterial infections", CURRENT OPINION IN PHARMACOLOGY, ELSEVIER SCIENCE PUBLISHERS, NL, vol. 8, no. 5, 1 October 2008 (2008-10-01), pages 582 - 592, XP025609336, ISSN: 1471-4892, [retrieved on 20080918], DOI: DOI:10.1016/J.COPH.2008.08.001
B. L. PODLOGAR ET AL: "Patents on tetracycline and tetracyline derivatives as antimicrobials: January 1998 - October 2002", EXPERT OPIN. THER. PATENTS, vol. 13, no. 4, 2003, pages 467 - 478, XP002636177
A. K . VERMA ET AL: "Antibiotic and non-antibiotic tetracycline patents: 2002 - 2007", EXPERT OPIN. THER. PATENTS, vol. 18, 2008, pages 69 - 82, XP002636178
Attorney, Agent or Firm:
ABELLEIRA, Susan, M. et al. (Brook Smith & Reynolds, P.C.,530 Virginia Rd.,P.O. Box 913, Concord MA, US)
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