Title:
TETRAHYDROISOQUINOLINE COMPOUND AS POTASSIUM CHANNEL MODULATOR AND PREPARATION AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2022/028548
Kind Code:
A1
Abstract:
A tetrahydroisoquinoline compound as a potassium channel modulator and preparation and application thereof. Specifically, the compound has the structure as shown in formula A. Formula (A)
Inventors:
LIANG BO (CN)
LIU GANG (CN)
CHEN HUANMING (CN)
LIU GANG (CN)
CHEN HUANMING (CN)
Application Number:
PCT/CN2021/110991
Publication Date:
February 10, 2022
Filing Date:
August 05, 2021
Export Citation:
Assignee:
SHANGHAI ZHIMENG BIOPHARMA INC (CN)
International Classes:
C07D217/04; A61K31/4375; A61K31/472; A61K31/4725; A61P25/04; A61P25/06; A61P25/08; A61P25/22; A61P25/24; A61P25/28; A61P25/32; A61P25/36; A61P27/16; A61P29/00; C07D401/04; C07D409/04; C07D471/04
Foreign References:
| CN103508960A | 2014-01-15 | |||
| CN107814785A | 2018-03-20 | |||
| CN110511220A | 2019-11-29 | |||
| CN107108556A | 2017-08-29 |
Other References:
SAMBROOK ET AL.: "Molecular Cloning: Laboratory Manual", 1989, COLD SPRING HARBOR LABORATORY PRESS
ZHAOBING GAO ET AL., JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 285, no. 36, 2010, pages 28322 - 28332
See also references of EP 4071138A4
ZHAOBING GAO ET AL., JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 285, no. 36, 2010, pages 28322 - 28332
See also references of EP 4071138A4
Attorney, Agent or Firm:
XU&PARTNERS, LLC. (CN)
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