Title:
TETRANOR-PGDM/PGJM SPECIFIC IMMUNOGENS, ANTIBODIES, TRACERS, ASSAY KITS AND METHODS FOR MAKING SAME
Document Type and Number:
WIPO Patent Application WO/2011/159735
Kind Code:
A3
Abstract:
Tetranor-PGDM/tetranor-PGJM-specific antibodies, immunogens used to generate them, the processes of their manufacture, and their uses in assay kits for detecting and quantifying tetranor-PGDM and tetranor-PGJM in biological fluids for determining biosynthesis of PGD2 in a subject or patient.
Inventors:
JOHNSON JEFFREY K (US)
MAXEY KIRK M (US)
TEW DANIEL J (US)
KORNILOV ANDRIY M (US)
MAXEY KIRK M (US)
TEW DANIEL J (US)
KORNILOV ANDRIY M (US)
Application Number:
PCT/US2011/040402
Publication Date:
April 05, 2012
Filing Date:
June 14, 2011
Export Citation:
Assignee:
CAYMAN CHEMICAL CO INC (US)
JOHNSON JEFFREY K (US)
MAXEY KIRK M (US)
TEW DANIEL J (US)
KORNILOV ANDRIY M (US)
JOHNSON JEFFREY K (US)
MAXEY KIRK M (US)
TEW DANIEL J (US)
KORNILOV ANDRIY M (US)
International Classes:
C07K14/47; C07K16/18; C07K19/00; G01N33/53
Domestic Patent References:
| WO1994004921A1 | 1994-03-03 | |||
| WO2009043015A1 | 2009-04-02 |
Other References:
SONG, W-L. ET AL.: "Tetranor PGDM, an abundant urinary metabolite reflects biosynthesis of prostaglandin D2 in mice and humans.", J. B. C, vol. 283, no. 2, 2008, pages 1179 - 1188
LEVINE, L.: "Antibodies to pharmacologically active molecules: specificities and some applications of antiprostaglandins.", PHARMACOL. REV., vol. 25, no. 2, 1973, pages 293 - 307
LEVINE, L.: "Antibodies to pharmacologically active molecules: specificities and some applications of antiprostaglandins.", PHARMACOL. REV., vol. 25, no. 2, 1973, pages 293 - 307
Attorney, Agent or Firm:
HAYS, Steven W. (LLPOne Oxford Centre, 38th Floor,301 Grant Stree, Pittsburgh Pennsylvania, US)
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